Dr Richard Mort

Lecturer

Profile

Dr. Richard Mort took up his post as Lecturer in Biomedicine at Lancaster University in October 2016. He specialises in imaging based methods to understand development, tissue homoeostasis and disease with a particular interest in the melanocyte lineage.

A Multi-stage Representation of Cell Proliferation as a Markov Process
Yates, C.A., Ford, M.J., Mort, R.L. 12/2017 In: Bulletin of Mathematical Biology. 79, 12, p. 2905-2928. 24 p.
Journal article

Osteoclast stimulation factor 1 (Ostf1) KNOCKOUT increases trabecular bone mass in mice
Vermeren, M., Lyraki, R., Wani, S., Airik, R., Albagha, O., Mort, R., Hildebrandt, F., Hurd, T. 12/2017 In: Mammalian genome : official journal of the International Mammalian Genome Society. 28, 11-12, p. 498-514. 17 p.
Journal article

Hierarchical patterning modes orchestrate hair follicle morphogenesis
Glover, J.D., Wells, K.L., Matthäus, F., Painter, K.J., Ho, W., Riddell, J., Johansson, J.A., Ford, M.J., Jahoda, C.A.B., Klika, V., Mort, R.L., Headon, D.J. 11/07/2017 In: Plos Biology. 15, 7, 31 p.
Journal article

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins
Hall, E.A., Nahorski, M.S., Murray, L.M., Shaheen, R., Perkins, E., Dissanayake, K.N., Kristaryanto, Y., Jones, R.A., Vogt, J., Rivagorda, M., Handley, M.T., Mali, G.R., Quidwai, T., Soares, D.C., Keighren, M.A., McKie, L., Mort, R.L., Gammoh, N., Garcia-Munoz, A., Davey, T., Vermeren, M., Walsh, D., Budd, P., Aligianis, I.A., Faqeih, E., Quigley, A.J., Jackson, I.J., Kulathu, Y., Jackson, M., Ribchester, R.R., von Kriegsheim, A., Alkuraya, F.S., Woods, C.G., Maher, E.R., Mill, P. 4/05/2017 In: American Journal of Human Genetics. 100, 5, p. 706-724. 19 p.
Journal article

Using approximate Bayesian computation to quantify cell–cell adhesion parameters in a cell migratory process
Ross, R.J.H., Baker, R.E., Parker, A., Ford, M.J., Mort, R.L., Yates, C.A. 10/03/2017 In: npj Systems Biology and Applications. 3, 1, 10 p.
Journal article

Using approximate Bayesian computation to quantify cell-cell adhesion parameters in a cell migratory process
Ross, R., Baker, R., Ford, M., Mort, R., Yates, C. 24/08/2016 In: Biorxiv. 26 p.
Journal article

Abnormal corneal epithelial maintenance in mice heterozygous for the micropinna microphthalmia mutation Mp
Douvaras, P., Dorà, N.J., Mort, R.L., Lodge, E.J., Hill, R.E., West, J.D. 08/2016 In: Experimental Eye Research. 149, p. 26-39. 14 p.
Journal article

Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model
Mort, R.L., Ross, R.J.H., Hainey, K.J., Harrison, O.J., Keighren, M.A., Landini, G., Baker, R.E., Painter, K.J., Jackson, I.J., Yates, C.A. 6/01/2016 In: Nature Communications. 7, 13 p.
Journal article

Maintenance of distinct melanocyte populations in the interfollicular epidermis
Glover, J.D., Knolle, S., Wells, K.L., Liu, D., Jackson, I.J., Mort, R.L., Headon, D.J. 07/2015 In: Pigment Cell and Melanoma Research. 28, 4, p. 476-480. 5 p.
Journal article

The melanocyte lineage in development and disease
Mort, R.L., Jackson, I.J., Patton, E.E. 1/04/2015 In: Development. 142, 7, p. 1387. 1 p.
Journal article

The melanocyte lineage in development and disease
Mort, R.L., Jackson, I.J., Patton, E.E. 15/02/2015 In: Development. 142, 4, p. 620-632. 13 p.
Journal article

Fucci2a: a bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice
Mort, R.L., Ford, M.J., Sakaue-Sawano, A., Lindstrom, N.O., Casadio, A., Douglas, A.T., Keighren, M.A., Hohenstein, P., Miyawaki, A., Jackson, I.J. 30/10/2014 In: Cell Cycle. 13, 17, p. 2681-2696. 16 p.
Journal article

Ex vivo culture of mouse embryonic skin and live-imaging of melanoblast migration
Mort, R.L., Keighren, M., Hay, L., Jackson, I.J. 19/05/2014 In: Journal of Sex Research. 87
Journal article

Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia
Douvaras, P., Mort, R.L., Edwards, D., Ramaesh, K., Dhillon, B., Morley, S.D., Hill, R.E., West, J.D. 13/08/2013 In: PLoS ONE. 8, 8, 18 p.
Journal article

A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy
Jadeja, S., Mort, R.L., Keighren, M., Hart, A.W., Joynson, R., Wells, S., Potter, P.K., Jackson, I.J. 1/05/2013 In: Investigative Ophthalmology and Visual Science. 54, 5, p. 3569-3578. 10 p.
Journal article

Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism
Li, A., Ma, Y., Jin, M., Mason, S., Mort, R.L., Blyth, K., Larue, L., Sansom, O.J., Machesky, L.M. 11/2012 In: Journal of Investigative Dermatology. 132, 11, p. 2610-2621. 12 p.
Journal article

Stem cells and corneal epithelial maintenance: insights from the mouse and other animal models
Mort, R.L., Douvaras, P., Morley, S.D., Dorà, N., Hill, R.E., Collinson, J.M., West, J.D. 21/07/2012 In: Mouse development. Berlin : Springer p. 357-94. 38 p. ISBN: 9783642304057. Electronic ISBN: 9783642304064.
Chapter

Normal X-inactivation mosaicism in corneas of heterozygous FlnaDilp2/+ female mice--a model of human filamin A (FLNA) diseases
Douvaras, P., Liu, W., Mort, R.L., McKie, L., West, K.M., Cross, S.H., Morley, S.D., West, J.D. 27/02/2012 In: BMC Research Notes. 5, 7 p.
Journal article

Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium
Kucerova, R., Dorà, N., Mort, R.L., Wallace, K., Leiper, L.J., Lowes, C., Neves, C., Walczysko, P., Bruce, F., Fowler, P.A., Rajnicek, A.M., McCaig, C.D., Zhao, M., West, J.D., Collinson, J.M. 18/01/2012 In: Molecular Vision. 18, p. 139-150. 12 p.
Journal article

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis
Lindsay, C.R., Lawn, S., Campbell, A.D., Faller, W.J., Rambow, F., Mort, R.L., Timpson, P., Li, A., Cammareri, P., Ridgway, R.A., Morton, J.P., Doyle, B., Hegarty, S., Rafferty, M., Murphy, I.G., McDermott, E.W., Sheahan, K., Pedone, K., Finn, A.J., Groben, P.A., Thomas, N.E., Hao, H., Carson, C., Norman, J.C., Machesky, L.M., Gallagher, W.M., Jackson, I.J., Van Kempen, L., Beermann, F., Der, C., Larue, L., Welch, H.C., Ozanne, B.W., Sansom, O.J. 22/11/2011 In: Nature Communications. 2, 9 p.
Journal article

Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression
Li, A., Ma, Y., Yu, X., Mort, R.L., Lindsay, C.R., Stevenson, D., Strathdee, D., Insall, R.H., Chernoff, J., Snapper, S.B., Jackson, I.J., Larue, L., Sansom, O.J., Machesky, L.M. 18/10/2011 In: Developmental Cell. 21, 4, p. 722-734. 13 p.
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Ex vivo live imaging of melanoblast migration in embryonic mouse skin
Mort, R.L., Hay, L., Jackson, I.J. 04/2010 In: Pigment Cell and Melanoma Research. 23, 2, p. 299-301. 3 p.
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Quantitative analysis of patch patterns in mosaic tissues with ClonalTools software
Mort, R.L. 12/2009 In: Journal of Anatomy. 215, 6, p. 698-704. 7 p.
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Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium
Mort, R.L., Ramaesh, T., Kleinjan, D.A., Morley, S.D., West, J.D. 7/01/2009 In: Developmental Biology. 9, 14 p.
Journal article

Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer
Mort, R.L., Mo, L., McEwan, C., Melton, D.W. 21/07/2003 In: British Journal of Cancer. 89, 2, p. 333-337. 5 p.
Journal article