Dr Sara Baldock

Experimental Officer in Microscopy and Nanofabrication

Research Overview

Professional Role

I am responsible for the Chemistry Department’s: Atomic Force Microscope (AFM), Scanning Electron Microscope (SEM) and the state-of-the-art 3D laser micro- and nano-fabrication system the Nanoscribe Photonic Professional GT.Equipment specifications can be found at:http://www.lancaster.ac.uk/chemistry/research/research-facilities/microscopy-and-nanofabrication/This instrumentation is also commercially available through the collaborative technology access program (cTAP):http://www.lancaster.ac.uk/chemistry/business/collaborative-technology-access-programme/

Research Overview

I have a background in Chemistry and Physics. My expertise is in the design, production, characterisation & application of micro- and nano-fabricated polymer and glass devices for microfluidic applications (electroseparations and electrochemical detection). Keywords: Two photon polymerisation, direct laser writing, photolithography, microfabrication, nanofabrication, scanning electron microscopy, atomic force microscopy, electrophoresis, isotachophoresis, voltammetry & conductivity detection.

Heparin and methionine oxidation promote the formation of apolipoprotein A-I amyloid comprising α-helical and β-sheet structures.
Townsend, D.J., Hughes, E., Hussain, R., Siligardi, G., Baldock, S.J., Madine, J., Middleton, D.A. 21/03/2017 In: Biochemistry. 56, 11, p. 1632-1644. 13 p.
Journal article

A miniaturized injection-moulded flow-cell with integrated conducting polymer electrodes for on-line electrochemical degradation of azo dye solutions
Mohammed Redha, Z., Abdulla Yusuf, H., Ahmed, H.A., Fielden, P.R., Goddard, N.J., Baldock, S.J. 5/02/2017 In: Microelectronic Engineering. 169, p. 16-23. 8 p.
Journal article

Determination of pb(II) by sequential injection/stripping analysis at all-plastic electrochemical fluidic cells with integrated composite electrodes
Kokkinos, C., Economou, A., Goddard, N., Fielden, P.R., Baldock, S.J. 1/06/2016 In: Talanta. 153, p. 170-176. 7 p.
Journal article

An analytical study of the electrochemical degradation of methyl orange using a novel polymer disk electrode
Yusuf, H.A., Redha, Z.M., Baldock, S.J., Fielden, P.R., Goddard, N.J. 5/01/2016 In: Microelectronic Engineering. 149, p. 31-36. 6 p.
Journal article

Microfluidic channel-assisted screening of hematopoietic malignancies
Mughal, F., Baldock, S.J., Karimiani, E.G., Telford, N., Goddard, N.J., Day, P.J.R. 03/2014 In: Genes, Chromosomes and Cancer. 53, 3, p. 255-263. 9 p.
Journal article

Miniaturised free flow isotachophoresis of bacteria using an injection moulded separation device
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Goodacre, R., O'Connor, R., Brown, B.J.T. 15/08/2012 In: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 903, p. 53-59. 7 p.
Journal article

Thiocyanate and nitrite analysis using miniaturised isotachophoresis on a planar polymer chip
Prest, J.E., Baldock, S.J., Beardah, M.S., Doyle, S.P., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 7/08/2011 In: The Analyst. 136, 15, p. 3170-3176. 7 p.
Journal article

Determination of the potassium content of explosive residues using miniaturised isotachophoresis
Prest, J.E., Beardah, M.S., Baldock, S.J., Doyle, S.P., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 11/2010 In: Electrophoresis. 31, 22, p. 3775-3782. 8 p.
Journal article

Systematic linearisation of a microfluidic gradient network with unequal solution inlet viscosities demonstrated using glycerol
Yusuf, H.A., Baldock, S.J., Fielden, P.R., Goddard, N.J., Mohr, S., Brown, B.J.T. 05/2010 In: Microfluidics and Nanofluidics. 8, 5, p. 587-598. 12 p.
Journal article

A miniaturised isotachophoresis method for magnesium determination
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 07/2009 In: Analytical and Bioanalytical Chemistry. 394, 5, p. 1299-1305. 7 p.
Journal article

Optical imaging and analytical modelling of the dynamic concentration gradient of viscous inlet solutions in a microfabricated network design
Yusuf, H.A., Baldock, S.J., Mohr, S., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 04/2009 In: Microelectronic Engineering. 86, 4-6, p. 1361-1364. 4 p.
Journal article

Hybrid microfluidic sensors fabricated by screen printing and injection molding for electrochemical and electrochemiluminescence detection
Redha, Z.M., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T., Haggett, B.G.D., Andres, R., Birch, B.J. 02/2009 In: Electroanalysis. 21, 3-5, p. 422-430. 9 p.
Journal article

Determination of chlorine containing species in explosive residues using chip-based isotachophoresis
Prest, J.E., Beardah, M.S., Baldock, S.J., Doyle, S.P., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 27/06/2008 In: Journal of Chromatography A. 1195, 1-2, p. 157–163. 7 p.
Journal article

Disposable electrochemical flow cells for catalytic adsorptive stripping voltammetry (CAdSV) at a bismuth film electrode (BiFE)
Naseri, N.G., Baldock, S.J., Economou, A., Goddard, N.J., Fielden, P.R. 06/2008 In: Analytical and Bioanalytical Chemistry. 391, 4, p. 1283-1292. 10 p.
Journal article

A versatile sample injection system for miniaturised isotachophoresis devices
Baldock, S.J., Fielden, P.R., Goddard, N.J., Kretschmer, H.R., Prest, J.E., Brown, B.J.T. 05/2008 In: Microelectronic Engineering. 85, 5-6, p. 1440-1442. 3 p.
Journal article

Novel microsystems for concentration gradient generation through computer optimization with validation using optical instrumentation
Yusuf, H.A., Baldock, S.J., Barber, R.W., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 05/2008 In: Microelectronic Engineering. 85, 5-6, p. 1265-1268. 4 p.
Journal article

Disposable injection-moulded cell-on-a-chip microfluidic devices with integrated conducting polymer electrodes for on-line voltammetric and electrochemiluminescence detection
Naseri, N.G., Baldock, S.J., Economou, A., Goddard, N.J., Fielden, P.R. 02/2008 In: Electroanalysis. 20, 4, p. 448-454. 7 p.
Journal article

Miniaturised isotachophoresis of DNA
Prest, J.E., Baldock, S.J., Day, P.J.R., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 13/07/2007 In: Journal of Chromatography A. 1156, 1-2, p. 154-159. 6 p.
Journal article

Free flow isotachophoresis in an injection moulded miniaturised separation chamber with integrated electrodes
Stone, V.N., Baldock, S.J., Croasdell, L.A., Dillon, L.A., Fielden, P.R., Goddard, N.J., Thomas, C.L.P., Brown, B.J.T. 2007 In: Journal of Chromatography A. 1155, 2, p. 199-205. 7 p.
Journal article

Rapid chloride analysis using miniaturised isotachophoresis
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Mohr, S., Brown, B.J.T. 30/06/2006 In: Journal of Chromatography A. 1119, 1-2, p. 183-187. 5 p.
Journal article

Inorganic arsenic and selenium determination using miniaturised isotachophoresis
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 11/2005 In: Microchimica Acta. 151, 3-4, p. 223-230. 8 p.
Journal article

Analysis of chloride, bromide and iodide using miniaturised isotachophoresis on a planar polymer chip
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 24/08/2005 In: The Analyst. 130, 10, p. 1375-1382. 8 p.
Journal article

Analysis of amino acids by miniaturised isotachophoresis
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Treves Brown, B.J. 8/10/2004 In: Journal of Chromatography A. 1051, 1-2, p. 221-226. 6 p.
Journal article

Use of miniaturised isotachophoresis on a planar polymer chip to analyse transition metal ions in solutions from metal processing plants
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Kalimeri, K., Brown, B.J.T., Zgraggen, M. 27/08/2004 In: Journal of Chromatography A. 1047, 2, p. 289-298. 10 p.
Journal article

Novel variable volume injector for performing sample introduction in a miniaturised isotachophoresis device
Baldock, S.J., Fielden, P.R., Goddard, N.J., Kretschmer, H.R., Prest, J.E., Brown, B.J.T. 9/07/2004 In: Journal of Chromatography A. 1042, 1-2, p. 181-188. 8 p.
Journal article

Integrated isotachophoresis in a miniaturised format for the separation of heavy metal cations
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 2004 In: Canadian Journal of Analytical Sciences and Spectroscopy. 49, 3, p. 129-135. 7 p.
Journal article

Determination of the ascorbate content of photographic developer solutions using miniaturised isotachophoresis on a planar chip
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 24/07/2003 In: The Analyst. 128, 9, p. 1131-1136. 6 p.
Journal article

Determination of inorganic selenium species by miniaturised isotachophoresis on a planar polymer chip
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 05/2003 In: Analytical and Bioanalytical Chemistry. 376, 1, p. 78-84. 7 p.
Journal article

Integrated moulded polymer electrodes for performing conductivity detection on isotachophoresis microdevices
Baldock, S.J., Fielden, P.R., Goddard, N.J., Prest, J.E., Brown, B.J.T. 21/03/2003 In: Journal of Chromatography A. 990, 1-2, p. 11-22. 12 p.
Journal article

Miniaturised isotachophoretic analysis of inorganic arsenic speciation using a planar polymer chip with integrated conductivity detection
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 2003 In: Journal of Chromatography A. 990, 1-2, p. 325-334. 10 p.
Journal article

Bidirectional isotachophoresis on a planar chip with integrated conductivity detection
Prest, J.E., Baldock, S.J., Fielden, P.R., Goddard, N.J., Brown, B.J.T. 9/10/2002 In: The Analyst. 127, 11, p. 1413-1419. 7 p.
Journal article

Determination of metal cations on miniaturised planar polymeric separation devices using isotachophoresis with integrated conductivity detection
Prest, J.E., Baldock, S.J., Fielden, P.R., Brown, B.J.T. 12/03/2001 In: The Analyst. 126, 4, p. 433-437. 5 p.
Journal article

Single electrode conductivity detection for electrophoretic separation systems
Prest, J.E., Baldock, S.J., Bektas, N., Fielden, P.R., Brown, B.J.T. 19/03/1999 In: Journal of Chromatography A. 836, 1, p. 59-65. 7 p.
Journal article

Isotachophoresis on planar polymeric substrates
Baldock, S.J., Bektas, N., Fielden, P.R., Goddard, N.J., Pickering, L.W., Prest, J.E., Snook, R.D., Brown, B.J.T., Vaireanu, D.I. 1998 In: Micro Total Analysis Systems ’98. Dordrecht : Kluwer p. 359-362. 4 p.
Paper