Dr Vilius Franckevicius


Research Overview

Our research programme lies at the heart of organic synthesis and contemporary metal catalysis, and focuses on the discovery and development of new waste-minimised and sustainable synthetic tools for the efficient assembly of organic molecules in an asymmetric manner. We are, in particular, interested in decarboxylative C–C bond formation methods, which, unlike traditional catalytic cross-coupling approaches, avoid the use of basic or harsh reaction conditions and, save for carbon dioxide, which is easily removable, do not generate stoichiometric amounts of by-products or harmful waste.

Catalytic decarboxylative alkenylation of enolates
Schroeder, S., Taylor, N., Jackson, P., Franckevicius, V. 19/07/2013 In: Organic letters. 15, 14, 4 p.

Copper-catalysed approach to spirocyclic oxindoles via a direct C-H, Ar-H functionalisation
Moody, C.L., Franckevicius, V., Drouhin, P., Klein, J.E.M.N., Taylor, R.J.K. 11/04/2012 In: Tetrahedron Letters. 53, 15, p. 1897-1899. 3 p.
Journal article

Asymmetric Decarboxylative Allylation of Oxindoles
Franckevicius, V., Cuthbertson, J.D., Pickworth, M., Pugh, D.S., Taylor, R.J.K. 19/08/2011 In: Organic letters. 13, 16, p. 4264-4267. 4 p.
Journal article

Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis
Evans, A.C., Longbottom, D.A., Matsuoka, M., Davies, J.E., Turner, R., Franckevicius, V., Ley, S.V. 2009 In: Organic & biomolecular chemistry. 7, 4, p. 747-760. 14 p.
Journal article

Aureggi, V., Franckevicius, V., Kitching, M.O., Ley, S.V., Longbottom, D.A., Oelke, A.J., Sedelmeier, G. 2008 In: Organic Syntheses. 85, p. 72-87. 16 p.
Journal article

Practical organocatalysis with (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles
Longbottom, D.A., Franckevicius, V., Kumarn, S., Oelke, A.J., Wascholowski, V., Ley, S.V. 2008
Scientific review

(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric organocatalysts of broad utility in organic synthesis
Longbottom, D.A., Franckevicius, V., Ley, S.V. 2007
Scientific review

8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction
Franckevicius, V., Longbottom, D.A., Turner, R.M., Ley, S.V. 4/10/2006 In: Synthesis-Stuttgart. 2006, 19, p. 3215-3223. 9 p.
Journal article

Practical synthesis of (S)-pyrrolidin-2-yl-1H-tetrazole, incorporating efficient protecting group removal by flow-reactor hydrogenolysis
Franckevicius, V., Knudsen, K., Ladlow, M., Longbottom, D., Ley, S. 4/04/2006 In: Synlett. 2006, 6, p. 889-892. 4 p.
Journal article

Structures of 2,4,6-tri-alpha-pyridyl-1,3,5-triazine complexes of the lanthanoid nitrates: A study in the lanthanoid contraction
Cotton, S.A., Franckevicius, V., Mahon, M.F., Ooi, L.L., Raithby, P., Teat, S.J. 6/03/2006 In: Polyhedron. 25, 4, p. 1057-1068. 12 p.
Journal article

Synthesis of medium-ring and iodinated biaryl compounds by organocuprate oxidation
Surry, D., Su, X., Fox, D., Franckevicius, V., Macdonald, S., Spring, D. 11/03/2005 In: Angewandte Chemie International Edition. 44, 12, p. 1870-1873. 4 p.
Journal article

Synthesis of complexes of 2,2 ': 6 ',2 ''-terpyridine and 1,10-phenanthroline with lanthanide thiocyanates; the molecular structures of [Ln(terpy)(2)(NCS)(3)] (Ln = Pr, Nd), [Nd(terpy)(2)(NCS)(3)]center dot 2EtOH and [Ln(phen)(3)(NCS)(3)]center dot EtOH (Ln = Pr, Nd)
Cotton, S.A., Franckevicius, V., How, R.E., Ahrens, B., Ooi, L.L., Mahon, M.F., Raithby, P.R., Teat, S.J. 1/06/2003 In: Polyhedron. 22, 11, p. 1489-1497. 9 p.
Journal article

Syntheses and structures of iron(III) complexes of simple N-donor ligands
Cotton, S.A., Franckevicius, V., Fawcett, J. 1/09/2002 In: Polyhedron. 21, 20, p. 2055-2061. 7 p.
Journal article

Benchmark compounds. Structures of cobalt(II) complexes of triphenylphosphine- and triphenylarsine oxides
Cotton, S.A., Franckevicius, V., Fawcett, J. 02/2002 In: Transition metal chemistry. 27, 1, p. 38-41. 4 p.
Journal article