Dr Andrew Fielding
Senior Lecture in Cancer ResearchResearch Overview
Cancer is a disease characterised by errors in cell cycle regulation, leading to uncontrolled cell proliferation. However, these errors also lead to cancer cells possessing unique phenotypes, such as centrosome amplification, which could potentially decrease their survival. In my laboratory we aim to understand these phenotypes and in turn target these to provide cancer-specific methods for inhibiting cell proliferation.
PhD Supervision Interests
I am always very happy to discuss MSc by Research and PhD projects, in the field of cancer cell biology. We are particularly interested in using novel therapies to specifically inhibit the growth of aggressive cancer types, such as triple-negative breast cancer and metastatic uveal melanoma. We are also interested in cell-cycle and cell migration defects in cancer. Can currently offer projects in several areas including: 1. Validation of novel cancer therapies in aggressive cancers. 2. Cell cycle defects in cancer 3. Understanding and targeting centrosome amplification in cancer. 4. The interplay between DNA damage, the cell cycle and centrosome amplification. Projects typically involve multiple techniques, including cell culture, fixed and live cell microscopy, cell growth assays and flow cytometry. Image analysis of high-content live cell imaging data is another technique used in some projects.
NWCR Summer Studentship Renewal
01/07/2021 → 30/09/2021
Research
Small molecule induced degradation of centrosome clustering proteins: development of a novel, cancer-specific therapeutic approach
27/01/2020 → 31/10/2023
Research
Investigating the thermosensitivity of cancer cell division dynamics: toward cancer thermotherapies?
01/07/2019 → 30/09/2020
Research
North West Cancer Research Lunesdale Committee Campus Visit
Types of Business and Community - Hosting of external, non-academic visitor
North West Cancer Research Fundraisers Departmental Visit
Types of Business and Community - Hosting of external, non-academic visitor
North West Melanoma Meeting
Symposium
North West Cancer Research Symposium 2023
Symposium
FURNESS STEM SHOW 2023
Other
FHM Promotion Workshop for academic staff
Participation in workshop, seminar, course
MSc by Research Viva: BLS
Examination
Lancaster mini melanocyte Symposium 2022
Participation in conference -Mixed Audience
External examiner for PhD viva
Examination
MSc by Research: Internal examiner
Examination
External examiner for PhD viva
Examination
MSc by Research viva: Internal examiner
Examination
Investigative Ophthalmology and Visual Science (Journal)
Publication peer-review
Chamber of Commerce BLS visit on behalf of NWCR
Participation in workshop, seminar, course
"Strawberry DNA" primary school visits, jointly hosted by NWCR researchers and the students union.
Other
MSc by research viva: Internal examiner
Examination
Keynote speaker on Biostatistics and Epidemiology: Cancer Course
Consultancy
Morecambe Carnival, "all about DNA" hands-on stand.
Festival/Exhibition/Concert
NW Ubiquitylation and Cell cycle Meeting
Other
Internal examiner for PhD candidate
Examination
Invited talk at NW DNA-repair network meeting
Invited talk
Campus in the City 2019
Festival/Exhibition/Concert
Talk at British Society of Cell Biology Annual Meeting
Invited talk
Prof Fred Currell, Director of Dalton Cumbria Facility, BLS visit and Departmental Seminar
Participation in workshop, seminar, course
Dalton Cumbrian Facility: Inaugral Biohealth meeting
Participation in conference -Mixed Audience
Internal Examiner for Lily Dixon, MSc by Research, FHM
Examination
NWCR Lunesdale Committee AGM
Other
"Strawberry DNA" primary school visits, jointly hosted by NWCR researchers and the students union.
Other
Ripley St Thomas: School Outreach
Other
Short talk at ARVO Ocular Oncogenesis Conference
Oral presentation
Work Experience in Cancer Research
Types of Public engagement and outreach - Festival/Exhibition
Talk at University of Liverpool NWCR Centre Seminar Series
Invited talk
The University of Liverpool
Visiting an external academic institution
NWCR/UoL hosted visit for Local Primary School
Types of Public engagement and outreach - Festival/Exhibition
Lab tours on behalf of North-West Cancer Research for Lancaster House Staff
Types of Public engagement and outreach - Festival/Exhibition
Invited talk at North-West Cancer Research Annual Symposium
Invited talk
Genome Stability Meeting
Participation in conference -Mixed Audience
Managing, motivating and developing your researchers
Participation in workshop, seminar, course
NWCR 70th Anniversary Award: Rising Star in Research
Prize (including medals and awards)
- Cancer Biology and Genome Stability