Our Research

Particular research areas within the ageing theme include:

  • Mechanisms of normal ageing using Drosophila as a model system
  • Age-related diseases, including neurodegenerative, joint and eye diseases
  • Palliative and end of life care
  • Place, health and wellbeing of ageing populations
  • Technologies for healthy ageing
  • Environmental/spatial epidemiology of cancer
  • Genome stability
  • Molecular mechanisms of carcinogenesis
  • Supportive and end of life care for those with cancer

Research successes

Notable research successes include:

  • Development of retro-inverted peptides as inhibitors of β-amyloid aggregation for the potential treatment of Alzheimer's disease
  • Development of α-synuclein as a biomarker for Parkinson's disease
  • Adoption of an ethical framework for good practice in telecare implementation by Age UK
  • Major revisions made to WHO policy document "Ensuring balance in national policies on controlled substances. Guidance for availability and accessibility of controlled medicines", arising from ATOME project. Document published free in 15 languages and distributed worldwide
  • Co-ordination of research and development at governmental level in 12 resource-poor countries in central and eastern Europe to remove barriers to adequate pain control
  • Cochrane Review on case management approaches to home support for people with dementia (Protocol)
  • Demonstration of an epidemiological link between paternal occupational social class and various childhood cancers
  • The publication of several papers that collectively shed new light on the mechanisms involved in maintaining genome stability
  • Our work on the biological effects of long wavelength ultraviolet (UV) radiation has informed the re-evaluation of the health risks of UV radiation and how these should be communicated by the International Agency for Research on Cancer and the International Commission for Non-Ionising Radiation Protection respectively
  • Researchers in the IOELC have authored resource-stratified guidelines for policy-makers on the supportive, palliative and end-of-life care of cancer patients in Asia
  • Anne Grinyer's book Palliative & End of Life Care for Children & Young People: Home, Hospice, Hospital, published by Blackwell in 2012, won an American Journal of Nursing Book of the Year Award.
  • Nancy Preston is developing an abdominal binder for malignant ascites (PI) from a Lancaster University Impact Award