An Initial Investigation to Assess the Cost-Effectiveness of the Colonix Device for the Detection of Colorectal Cancer

Client: Sheffield School for Health and Related Research (ScHARR)
Student: Jessica Heady
Supervisor: John Ranyard (MSc OR Project)


Colorectal cancer is registered as the underlying cause of approximately 15,000 deaths in England and Wales each year and it accounts for over ten percent of all cancer deaths This project is an initial investigation into the evaluation of a new device, ‘Colonix’, for use as an early diagnostic or screening tool for colorectal cancer. It is part of an on-going study, which will assess the costs and benefits of introducing the device into the health care system. Three stages were involved:

  • Stage One involved eliciting the current pathway for symptomatic patients of colorectal cancer and developing a visual representation of this pathway. This enabled the identification of the potential roles where Colonix has the potential to be clinically and cost-effective.
  • Stage Two included the development and populating of a quantitative decision-analytical model based on the output of Stage 1 to estimate the potential clinical- and cost-effectiveness of Colonix.
  • Stage Three examined the current evidence base concerning the costs and benefits. This allowed the identification of areas where future research is required and the further modelling necessary to complete the cost effectiveness analysis of the device.

These initial results indicated that colonic examination using the Colonix device would be quicker and less intrusive than many of the currently available diagnostic tests. Furthermore, the introduction of Colonix may be cost-saving and there may be a role for Colonix alongside colonoscopy within a secondary care setting.