Dr Lisa Hampson

Lecturer - Maths and Statistics, MRC Career Development Award Fellow

Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children
Hampson, L.V., Fisch, R., Van, L.M., Jaki, T.F. 10/02/2017 In: Statistics in Medicine. 36, 3, p. 426-441. 16 p.
Journal article

'Threshold crossing': a useful way to establish the counterfactual in clinical trials?
Eichler, H., Bloechl-Daum, B., Bauer, P., Bretz, F., Brown, J., Hampson, L.V., Honig, P., Krams, M., Leufkens, H., Lim, R., Lumpkin, M., Murphy, M., Pignatti, F., Posch, M., Schneeweiss, S., Trusheim, M., Koenig, F. 12/2016 In: Clinical Pharmacology & Therapeutics. 100, p. 699-712. 13 p.
Journal article

Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation
Wadsworth, I., Jaki, T.F., Sills, G.J., Appleton, R., Cross, J.H., Marson, A.G., Martland, T., McLellan, A., Smith, P.E.M., Pellock, J.M., Hampson, L.V. 11/2016 In: CNS Drugs. 30, 11, p. 1011-1017. 7 p.
Journal article

Planification d’un essai randomisé bayésien avec critère de survie: spécification du modèle incorporant les données historiques
Brard, C., Hampson, L.V., Le Deley, M., Le Teuff, G. 7/05/2016
Meeting abstract

Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods
Wadsworth, I., Hampson, L.V., Jaki, T.F. 17/03/2016 In: Statistical Methods in Medical Research.
Journal article

Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection
Jaki, T., Hampson, L. 20/02/2016 In: Statistics in Medicine. 35, 4, p. 522-533. 12 p.
Journal article

Elicitation of expert prior opinion: application to the MYPAN trial in childhood polyarteritis nodosa
Beresford, M.W., Bracaglia, C., Caldas, A., Cimaz, R., Dehoorne, J., Dolezalova, P., Friswell, M., Jelusic, M., Marks, S.D., Martin, N., McMahon, A., Peitz, J., van Royen-Kirkhof, A., Soylemezoglu, O., Brogan, P., MYPAN Vasculitis Expert Group 30/03/2015 In: PLoS ONE. 10, 3, 14 p.
Journal article

Optimising the data combination rule for seamless phase II/III clinical trials
Hampson, L., Jennison, C. 01/2015 In: Statistics in Medicine. 34, 1, p. 39-58. 20 p.
Journal article

Bayesian methods for the design and interpretation of clinical trials in very rare diseases
Hampson, L., Whitehead, J., Eleftheriou, D., Brogan, P. 30/10/2014 In: Statistics in Medicine. 33, 24, p. 4186-4201. 16 p.
Journal article

Bridging the gap: a review of dose investigations in paediatric investigation plans
Hampson, L., Herold, R., Posch, M., Saperia, J., Whitehead, A. 10/2014 In: British Journal of Clinical Pharmacology. 78, 4, p. 898-907. 10 p.
Journal article

R software to accompany "Bayesian methods for the design and interpretation of clinical trials in very rare diseases".
Hampson, L., Whitehead, J. 2014
Software

Exercise and self-management for people with chronic knee, hip or lower back pain: a cluster randomised controlled trial of clinical and cost-effectiveness. Study protocol
Walsh, N., Cramp, F., Palmer, S., Pollock, J., Hampson, L., Gooberman-Hill, R., Green, C., Jones, L., Phillips, S., Johnson, L., Hurley, M. 12/2013 In: Physiotherapy. 99, 4, p. 352-357. 6 p.
Journal article

Cost-utility analysis conducted alongside randomized controlled trials: Are economic end points considered in sample size calculations and does it matter?
Hollingworth, W., McKell-Redwood, D., Hampson, L., Metcalfe, C. 02/2013 In: Clinical Trials. 10, 1, p. 43-53. 11 p.
Journal article

Group sequential tests for delayed responses
Hampson, L., Jennison, C. 01/2013 In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 75, 1, p. 3-54. 52 p.
Journal article

Incorporating prognostic factors into causal estimators: a comparison of methods for RCTs with a time to event outcome
Hampson, L., Metcalfe, C. 20/11/2012 In: Statistics in Medicine. 31, 26, p. 3073-3088. 16 p.
Journal article

C Code to design error spending tests for delayed responses
Hampson, L., Jennison, C. 3/09/2012
Software

A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints .
Whitehead, J., Hampson, L., Zhou, Y., Ledent, E., Pereira, A. 11/2007 In: Journal of Biopharmaceutical Statistics. 17, 6, p. 1117-1129. 13 p.
Journal article