Claire Tinker

Associate Lecturer, PhD student

Thesis Title

The Nanostucture of Amyloid Fibres

Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species
Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B., Allsop, D. 25/04/2014 In: Journal of Biological Chemistry. 289, p. 12052-12062. 11 p.
Journal article

Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
Tinker-Mill, C., Mayes, J., Allsop, D., Kolosov, O. 2014 In: Scientific Reports. 4, 7 p.
Journal article

A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's Disease
Parthsarathy, V., McClean, P.L., Hölscher, C., Taylor, M., Tinker, C., Jones, G., Kolosov, O., Salvati, E., Gregori, M., Masserini, M., Allsop, D. 2013 In: PLoS ONE. 8, 1, 11 p.
Journal article

Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signalling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells
Parr-Sturgess, C.A., Tinker, C.L., Hart, C.A., Brown, M.D., Clarke, N.W., Parkin, E.T. 10/2012 In: Molecular cancer research : MCR. 10, 10, p. 1282-1293. 12 p.
Journal article

Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres
Grishin, I., Tinker, C., Allsop, D., Robson, A., Kolosov, O. 2012 In: NSTI-Nanotech 2012. Santa Clara, USA : CRC PRESS-TAYLOR & FRANCIS GROUP p. 110-113. 4 p.
Paper