# # Data extracted from a larger, and confidential, set of clinical trial data from a randomised # clinical trial of drug treatments for schizophrenia # # Response is a measure of severity of symptoms # # Measurements (columns 2 to 7) were made at weeks 0, 1, 2, 4, 6, 8 post-randomisation # Treatments (column 8) were a placebo and two active agents # Remaining columns: # n.obs: number of non-missing measurements # surv.time: imputeds dropout time # cens.ind: 0=non-informative dropout, 1=informative dropout # "indv" "Y.t0" "Y.t1" "Y.t2" "Y.t4" "Y.t6" "Y.t8" "treat" "n.obs" "surv.time" "cens.ind" "1" 1 91 NA NA NA NA NA 1 1 0.704 0 "2" 2 72 NA NA NA NA NA 2 1 0.74 0 "3" 3 108 110 NA NA NA NA 1 2 1.121 1 "4" 4 106 93 NA NA NA NA 1 2 1.224 1 "5" 5 77 80 NA NA NA NA 1 2 1.303 0 "6" 6 120 133 NA NA NA NA 1 2 1.541 1 "7" 7 113 130 NA NA NA NA 1 2 1.983 1 "8" 8 101 134 NA NA NA NA 2 2 1.035 1 "9" 9 97 97 NA NA NA NA 2 2 1.039 0 "10" 10 97 118 NA NA NA NA 2 2 1.116 1 "11" 11 96 90 NA NA NA NA 2 2 1.193 1 "12" 12 76 76 NA NA NA NA 2 2 1.238 0 "13" 13 99 123 NA NA NA NA 2 2 1.318 1 "14" 14 111 122 NA NA NA NA 2 2 1.489 1 "15" 15 120 130 NA NA NA NA 2 2 1.502 1 "16" 16 91 86 NA NA NA NA 2 2 1.597 1 "17" 17 105 135 NA NA NA NA 2 2 1.804 1 "18" 18 113 118 NA NA NA NA 2 2 1.961 1 "19" 19 81 71 NA NA NA NA 3 2 1.13 0 "20" 20 119 118 NA NA NA NA 3 2 1.16 0 "21" 21 77 94 NA NA NA NA 3 2 1.276 1 "22" 22 100 86 NA NA NA NA 3 2 1.565 1 "23" 23 67 108 NA NA NA NA 3 2 1.795 1 "24" 24 127 98 152 NA NA NA 1 3 2.136 1 "25" 25 161 116 85 NA NA NA 1 3 3.096 1 "26" 26 87 92 103 NA NA NA 1 3 3.221 1 "27" 27 73 87 91 NA NA NA 1 3 3.922 0 "28" 28 118 116 153 NA NA NA 2 3 2.062 1 "29" 29 92 72 78 NA NA NA 2 3 2.104 1 "30" 30 73 74 68 NA NA NA 2 3 2.201 1 "31" 31 112 112 117 NA NA NA 2 3 2.5 1 "32" 32 90 100 113 NA NA NA 2 3 2.554 1 "33" 33 60 93 116 NA NA NA 2 3 2.714 1 "34" 34 81 114 135 NA NA NA 2 3 3.066 1 "35" 35 93 86 94 NA NA NA 2 3 3.154 1 "36" 36 94 107 104 NA NA NA 3 3 2.423 1 "37" 37 104 106 102 NA NA NA 3 3 2.496 1 "38" 38 87 87 92 NA NA NA 3 3 2.676 1 "39" 39 75 52 46 NA NA NA 3 3 2.684 0 "40" 40 65 57 62 NA NA NA 3 3 3.055 0 "41" 41 84 80 72 NA NA NA 3 3 3.71 1 "42" 42 75 92 117 NA NA NA 3 3 3.794 1 "43" 43 102 109 111 108 NA NA 1 4 4.34 1 "44" 44 84 70 55 74 NA NA 1 4 4.416 1 "45" 45 99 98 92 112 NA NA 1 4 4.705 1 "46" 46 75 70 69 71 NA NA 1 4 4.708 0 "47" 47 84 99 105 98 NA NA 1 4 4.858 1 "48" 48 107 84 100 122 NA NA 1 4 5.003 1 "49" 49 129 113 116 114 NA NA 1 4 5.253 1 "50" 50 64 68 66 106 NA NA 1 4 5.334 1 "51" 51 79 91 73 89 NA NA 1 4 5.538 1 "52" 52 120 103 86 111 NA NA 1 4 5.603 1 "53" 53 98 98 96 80 NA NA 1 4 5.612 0 "54" 54 94 98 111 110 NA NA 1 4 5.864 1 "55" 55 87 104 95 99 NA NA 2 4 4.277 1 "56" 56 80 84 77 85 NA NA 2 4 4.696 1 "57" 57 90 74 74 92 NA NA 2 4 4.733 1 "58" 58 91 90 90 104 NA NA 2 4 5.148 1 "59" 59 71 96 96 97 NA NA 2 4 5.309 0 "60" 60 123 113 104 121 NA NA 2 4 5.57 0 "61" 61 78 84 91 107 NA NA 2 4 5.898 1 "62" 62 83 92 88 100 NA NA 3 4 4.16 1 "63" 63 76 54 51 65 NA NA 3 4 4.412 1 "64" 64 106 102 95 95 NA NA 3 4 4.996 1 "65" 65 95 87 101 104 NA NA 3 4 5.565 1 "66" 66 108 100 74 72 NA NA 3 4 5.918 0 "67" 67 87 83 89 98 107 NA 1 5 6.161 1 "68" 68 110 95 92 103 93 NA 1 5 6.313 1 "69" 69 74 60 54 49 45 NA 1 5 7.978 0 "70" 70 100 90 91 90 98 NA 2 5 6.099 1 "71" 71 86 94 86 93 109 NA 2 5 6.707 1 "72" 72 64 72 65 64 80 NA 2 5 6.789 0 "73" 73 84 60 94 82 97 NA 2 5 7.168 1 "74" 74 96 85 88 114 100 NA 2 5 7.182 1 "75" 75 121 103 84 62 144 NA 2 5 7.586 1 "76" 76 107 111 95 97 109 NA 2 5 7.785 1 "77" 77 70 57 57 52 47 NA 3 5 6.801 0 "78" 78 113 102 93 111 106 NA 3 5 7.017 0 "79" 79 100 54 53 58 44 NA 3 5 7.299 0 "80" 80 124 107 115 135 152 NA 3 5 7.3 1 "81" 81 105 74 89 75 89 NA 3 5 7.343 1 "82" 82 140 109 76 63 54 NA 3 5 7.644 0 "83" 83 93 90 91 94 102 109 1 6 8.001 1 "84" 84 60 79 55 58 65 51 1 6 8.002 0 "85" 85 98 78 64 55 57 62 1 6 8.002 0 "86" 86 90 96 86 78 78 86 1 6 8.002 0 "87" 87 123 126 104 101 94 93 1 6 8.002 0 "88" 88 102 119 112 98 90 80 1 6 8.002 0 "89" 89 83 73 82 80 76 86 1 6 8.002 0 "90" 90 60 52 49 45 46 50 1 6 8.002 0 "91" 91 75 79 76 79 86 91 1 6 8.002 0 "92" 92 78 74 62 60 73 82 1 6 8.002 0 "93" 93 71 73 71 61 56 58 1 6 8.002 0 "94" 94 110 106 115 131 128 125 1 6 8.002 0 "95" 95 98 102 85 86 101 94 1 6 8.002 0 "96" 96 83 80 88 85 85 79 1 6 8.002 0 "97" 97 105 53 53 44 44 44 1 6 8.002 0 "98" 98 84 67 80 67 77 74 1 6 8.002 0 "99" 99 104 75 73 76 75 71 1 6 8.002 0 "100" 100 105 100 109 91 95 69 1 6 8.002 0 "101" 101 64 62 82 83 74 65 1 6 8.002 0 "102" 102 93 97 104 107 94 98 1 6 8.002 0 "103" 103 73 75 65 64 66 62 1 6 8.002 0 "104" 104 88 60 49 65 46 47 1 6 8.002 0 "105" 105 77 82 73 63 52 56 1 6 8.002 0 "106" 106 107 48 73 75 54 56 1 6 8.002 0 "107" 107 77 82 70 66 60 55 1 6 8.002 0 "108" 108 106 76 75 84 88 88 2 6 8.001 1 "109" 109 72 64 53 60 98 98 2 6 8.002 0 "110" 110 113 105 116 95 113 111 2 6 8.002 0 "111" 111 89 90 66 76 101 113 2 6 8.002 0 "112" 112 72 57 57 53 55 48 2 6 8.002 0 "113" 113 95 110 107 86 95 108 2 6 8.002 0 "114" 114 77 57 64 52 52 47 2 6 8.002 0 "115" 115 84 93 75 79 79 73 2 6 8.002 0 "116" 116 132 138 110 119 110 106 2 6 8.002 0 "117" 117 94 81 86 84 81 84 2 6 8.002 0 "118" 118 63 66 39 58 73 95 2 6 8.002 0 "119" 119 96 82 73 85 81 89 2 6 8.002 0 "120" 120 67 77 85 113 122 106 2 6 8.002 0 "121" 121 90 85 96 100 89 95 2 6 8.002 0 "122" 122 72 71 62 61 59 57 2 6 8.002 0 "123" 123 73 88 92 77 72 72 2 6 8.002 0 "124" 124 101 63 67 87 63 62 3 6 8.002 0 "125" 125 76 56 50 43 43 40 3 6 8.002 0 "126" 126 72 69 77 70 75 72 3 6 8.002 0 "127" 127 135 62 84 66 42 70 3 6 8.002 0 "128" 128 108 84 95 89 92 116 3 6 8.002 0 "129" 129 76 76 77 70 85 82 3 6 8.002 0 "130" 130 67 74 70 68 66 99 3 6 8.002 0 "131" 131 110 87 95 61 56 59 3 6 8.002 0 "132" 132 137 85 56 60 49 59 3 6 8.002 0 "133" 133 101 65 44 36 33 37 3 6 8.002 0 "134" 134 98 95 91 91 89 93 3 6 8.002 0 "135" 135 95 88 90 61 70 70 3 6 8.002 0 "136" 136 78 60 61 49 55 52 3 6 8.002 0 "137" 137 82 79 73 68 64 66 3 6 8.002 0 "138" 138 92 96 81 75 92 95 3 6 8.002 0 "139" 139 70 66 63 55 46 57 3 6 8.002 0 "140" 140 62 60 56 54 53 54 3 6 8.002 0 "141" 141 60 52 55 46 39 42 3 6 8.002 0 "142" 142 93 96 84 85 98 78 3 6 8.002 0 "143" 143 79 86 91 66 57 106 3 6 8.002 0 "144" 144 113 99 98 84 98 95 3 6 8.002 0 "145" 145 74 60 55 69 58 50 3 6 8.002 0 "146" 146 96 78 77 77 117 114 3 6 8.002 0 "147" 147 74 62 70 58 59 57 3 6 8.002 0 "148" 148 81 84 78 54 54 53 3 6 8.002 0 "149" 149 96 75 67 74 74 93 3 6 8.002 0 "150" 150 89 87 82 76 61 64 3 6 8.002 0