High-Resolution NMR Spectroscopy in Inhomogeneous B₀ and B₁ Fields by Two-Dimensional Correlation

Abstract
Recently, there has been much interest in methods for obtaining high-resolution NMR spectra in inhomogeneous B₀ and B₁ fields and in their application to so-called "ex situ" spectroscopy, where the sample and magnet/probe assembly are spatially separated. Here we discuss the implementation of the well-known two-dimensional nutation experiment as a method for correlating B₀ and B₁ inhomogeneities and, hence, achieving a high-resolution NMR spectrum. The advantages of this approach lie in its simplicity, its spatial ("depth") resolution, and in its not requiring a linear correlation of fields, i.e., B₀ = αB₀ + k, across the sample.