The aim of this module is to provide students with the skills they need to begin their future careers. The module will enhance career awareness, develop oral communications skills and develop CV and cover letter writing. Workshops include sessions on LinkedIn, information skills, assessment centres, interview techniques and entrepreneurship.

This module aims to provide a foundation in the core techniques utilised in protein purification.

Each week the lectures and practicals lead students through the variety of techniques used to purify proteins. The lectures provide students with an understanding of the biochemical methods commonly used and their significance within a protein purification strategy. Practicals will be tightly linked to the lectures, with students being required to follow a purification strategy over the course of the module. Starting with a mixture of proteins, students are set the task of purifying one of the proteins on the basis of their biochemical properties.

This module has four core topics that direct students through the purification process. They are:

• Introduction to protein purification and bulk preliminary purification techniques
• Chromatography techniques for protein purification
• Protein and enzyme assay techniques
• Gel electrophoresis and associated techniques.

This module is an introduction to cellular biochemistry focusing on the core pathways of intermediary metabolism which are central to cellular function. Specifically, it focuses on two related and key areas of biochemistry. The first is enzymology; how do proteins function as biological catalysts and how are chemical reactions controlled within a cell? Students will investigate how the many chemical reactions which participate in metabolism are accurately regulated and organised.

The second is cellular metabolism; particularly, how do cells obtain energy from their surroundings to maintain their complex order?

The module will cover several seminal and Nobel Prize winning research topics including a detailed look at the key reactions of the citric acid cycle and the coupling of electron transport, proton pumping and ATP synthesis. The concepts and areas of biochemistry covered will be further illustrated by reference to the pathological state and human diseases which result from specific malfunctions in biochemical pathways and reactions.

This module provides a comprehensive introduction to the basics of bioinformatics. The laboratory sessions will introduce students to software for sequence manipulation, genome visualization, phylogenetics, searching for related sequences using BLAST, primer design, structural biology and more. A lab manual written specially for the module is used to guide students step-by-step through learning the software.

Each student is assigned a virus genome sequence to which they will apply the techniques learned in the lab sessions to produce a coursework portfolio. By the end of the module, students will be prepared for more advanced bioinformatics techniques that they will encounter in third and fourth year modules, and which may also be of use to them in their dissertation projects.

This module explores the interactions that take place both within and between cells and which allow them to perform their function in the whole organism. Students will consider five key topics within cell biology:

• The methods used to study cells and the dynamic nature of the cytoskeleton
• The mechanisms and physiological significance of transport across membranes
• The mechanisms involved in cells receiving and acting upon information from outside of the cell
• The mechanisms of development of whole organisms, examining how individual cells become committed to a particular function as development occurs
• The regulation of the cell cycle, growth, and development. We will illustrate these topics using examples drawn from a range of biological system.

This laboratory-based module provides both a theoretical and experimental basis for further studies and research in cell biology. It will enable students to gain experience in a range of laboratory techniques including: handling mammalian cells, cell signalling, identification of subcellular molecular localisation by immunofluorescent microscopy, and cell cycle analysis by flow cytometry.

The module is delivered through mixed media platforms such as lectures and videos, with consolidation of the practicals in a final overarching data analysis workshop. Students will be able to apply these skills to design and carry out experiments for their own subsequent research projects.

This module introduces advanced techniques of eukaryotic recombinant DNA technology, DNA sequencing, genomics and functional genomics. Bioinformatics, the computer-based analysis of data that result from genome sequencing and the genomic approaches to understanding gene function and expression are introduced and developed in the workshops. The module practicals provide hands-on experience of quantitative gene expression analysis employing widely used state of the art PCR (polymerase chain reaction) based technology.

Students will gain knowledge and understanding of these techniques, which will provide the basis for the informed reading and comprehension of primary experimental biological research literature required for subsequent undergraduate research projects. These technologies underpin an increasing proportion of modern biological research, particularly in the Biomedical disciplines and form the basis for rapidly developing applications in the field of personalised medicine.

Environmental Physiology "crosses the great divide" between animal and plant biology. The scope of this module is broad, extending from the consequences of environmental change on human health to communication between plants. It explores the whole-organism responses of animals and plants to light, to pollution and to disease-causing micro-organisms. It goes on to consider how such responses are controlled and co-ordinated, and how information is communicated between individuals in both animals and plants.

The unifying theme of this module is the central role of physiology in determining a wide range of biological responses, with the overall aim of providing an integrated understanding of the mechanisms by which both animals and plants cope with their environment. Students will gain an appreciation of the complex interactions between plants and animals and their natural environments, and particularly the notion of phenotypic plasticity. Practical work will develop laboratory skills, and assessment will develop skills in literature searching, data analysis, writing and argument.

Students will develop a sophisticated skillset, including the ability to describe mechanisms by which plants and animals perceive environmental signals and co-ordinate their responses to them, as well as being able to describe the effects of ultraviolet light on animals and plants and the mechanisms for protection from its damaging effects. In addition, students will gain the necessary experience required to show how various environmental pollutants affect the health of plants and humans, and will be knowledgeable of the various forms of innate immunity in animals, whilst gaining awareness of the conservation of anti-microbial defence mechanisms during evolution. Finally, students will be able to explain how plants resist attack by herbivorous insects and pathogenic microorganisms.

Evolution is the fundamental concept in biology and an understanding of its processes and effects are important for biologists in all disciplines. The module aims to show how the morphology and behaviour of animals and plants is adapted to their environment through interactions with their own and other species, including competitors, parasites, predators and prey, and relatives. Students will explore the concept of adaptation to natural and sexual selection pressures at the level of the individual and the effects on the wider population.

Students will gain the ability to describe the roles that variation, heritability and selection play in the evolutionary process, along with a developed understanding of how numerical changes in population occur, and enhanced knowledge of how to analyse such shifts in order to make predictions about future changes. This module will also reinforce students’ understanding of the application of theoretical models, the changing effects of costs and behaviours due to circumstance, and how conflicts of interest might influence the reproductive success of individuals.

Students taking this module will gain a range of transferable skills including: report writing, data analysis and presentation, team working, verbal presentation, summarising technical texts and design of scientific enquiries.

The aim of this module is to introduce students to understanding the scientific method, designing experiments, and collecting data in an unbiased scientific manner, analysing it using robust statistical techniques and presenting findings in a clear and concise form. Students will be provided with the skills they will need to successfully complete their dissertation projects. They are encouraged to critically appraise information, conduct a wide range of statistical analyses and to present and critically analyse data.

Students will be able to relate the notion of the scientific method to their own scientific endeavour, and will gain the level of knowledge required to measure, describe and discuss the varieties of environmental and ecological systems in the study of natural systems.

Students will learn to design and execute experiments which distinguish effectively between variation due to experimental effects and underlying uncontrolled variation, and will also understand the application of statistical tests to analyse data, taking into account the underlying assumptions of those tests, as well as the uses of computer based statistical packages, such as SPSSx) to analyse data. Critical skills developed on this module will enable students to report their findings in a style appropriate for their audience.

Employers expect graduate biologists, especially those aiming for careers as field biologists or ecologists, to have gained experience of basic field biology skills and common survey techniques. This module offers an introduction to the fieldwork and methodology relevant for conducting ecological surveys. Students are taken through a habitat and biodiversity survey, and will develop skills in several areas, such as species identification, monitoring bird breeding parameters, moth trapping, and small mammal trapping.

The weeklong intensive course will take place in the local area and the work will mostly be conducted outdoors. Students will take part in two off-campus excursions, for example, to a species-rich meadow in the Yorkshire Dales, and to sites of highly diverse insect communities in the Morecambe Bay region to see Fritillary butterflies. They will also gain the ability to identify appropriate sampling methods and apply them in the field, as well as developing transferable abilities such as report writing, teamwork, observation skills and safety awareness.

This module takes a molecular approach to understanding heredity and gene function in organisms ranging from bacteria to man. It begins by reviewing genome diversity and how genomes are replicated accurately, comparing and contrasting replication processes in bacteria and man. The module discusses in detail molecular mechanisms, particularly those that ensure information encoded in the genome is transcribed and translated appropriately to produce cellular proteins.

Students will focus on the importance of maintaining genome stability and damaging effects of mutations in the genome on human health. Examples are drawn from a range of inherited genetic diseases such as phenylketonuria and sickle cell anaemia, paying particular focus to how mutations in key genes are driving cancer development.

Teaching is delivered by a series of lectures supported by varied practical work, workshops, guided reading and online resources. Laboratory practicals include investigating how exposure of bacteria to ultraviolet light induces mutations – providing a model for understanding how skin cancer may develop as a consequence of excessive sun exposure.

This course examines the relationship between microbe and host; with particular focus on bacterial and viral pathogens. The diversity of structure, function and metabolism of bacteria, in relation to their role as a cause of disease, is explored and practical skills in bacteriology are introduced. Morphology and reproductive strategies of viruses are examined and methods for controlling viral infections by vaccination or anti-viral therapies are described. The course introduces principles of clinical microbiology by focusing on epidemiology, diagnosis, treatment of infection and host immune defences. The theme is one of "emergence" illustrating how some new infections have come to be a problem in health care and the importance of protective commensal microbes. The laboratory classes focus on diagnostic processes and illustrate the contribution which the microbiology laboratory can make to clinical decision making and epidemiology. This course also deals with the way in which pathogens (mainly bacteria) survive, and sometimes grow, in the environment and the implications this has for health in the community. The course is given in collaboration with health service consultants and workers from the University Hospitals of Morecambe Bay NHS Trust.

When we look at ourselves in the mirror the last thing we consider is that we are only 10% human due to our body comprising ten times more bacterial cells than human cells! There is no mistaking the importance of our bacterial communities in maintaining our proper functioning, eg digesting food, but microbes also cause disease and it is this that normally attracts media attention.

The ‘good vs bad’ nature of microbes is covered in the module Medical Microbiology (the pre-requisite to this module) together with methods for controlling exposure to pathogens; particularly in a hospital setting. But what about the household setting? How dangerous are the microbes living on your household surfaces (including your toothbrush!)? Do disinfectants really kill 99.9% of germs (as stated by all manufacturers)? These questions, and others, are addressed in this module whilst students learn the essential practical techniques necessary to work in both industrial and hospital laboratories. The module also explores the use of microbes as artistic media in the up and coming field of BioArt.

Recent emphasis on global change and biodiversity has raised awareness of the importance of species and their interactions in determining how sustainable our lifestyle is. This module explores the factors that drive population and community dynamics, with a strong focus on multi-trophic interactions and terrestrial ecosystems.

Students will be introduced to population ecology and will discover the abiotic factors that regulate populations, life history strategies of populations, competitive interactions within populations, and meta-population dynamics, in addition to an understanding of how species interact both within and across trophic levels. The module exposes students to the belowground system and will look at how the species interactions and soil communities discussed impact on community structure and dynamics. The module aims to give students a fundamental understanding of ecology - such knowledge is essential for informing conservation and sustainable land-use practices, and efforts to mitigate climate change.

In order to complete this module, students will develop the ability to outline the primary factors that drive population dynamics, whilst critically discussing examples, and will reinforce their understanding of the implications of species interactions for community dynamics. Students will also gain a critical awareness of biotic responses and their contribution to climate change.

The aim of this module is to build on knowledge gained in earlier first year modules: Anatomy and Tissue Structure and Human Physiology. Students will focus on four weekly themes: heart and circulation; muscle and fatigue; nervous system and the urinary system. Students independently learn theoretical background information using online and text-based resources, supported by weekly case study discussions during seminars. Muscle electrical activity and fatigue, ECG and nerve conduction velocity will be explored through experimentation on student volunteers and online simulations.

This module aims to provide students with broad understanding of the discipline of conservation biology. The module starts by defining biodiversity, discussing its distribution in space and time, and its value to humankind, before examining the key anthropogenic threats driving recent enhanced rates of biodiversity loss. The module then focuses on the challenges for conservation of biodiversity at several levels of the biological hierarchy: genes, species, communities and ecosystems, and the techniques used by conservationists at these levels. The final part of the module looks at the practice of conservation through discussion of prioritisation, reserve design and national and international conservation policy and regulation.

Students will develop a range of skills including the ability to discuss the principle threats to global biodiversity and the rationale for biodiversity conservation, in addition to application of a range of metrics to quantify biodiversity. Students will gain a critical understanding of the various approaches to conserving genetic, species and ecosystem diversity, as well as an enhanced knowledge of quantification of popularisation approaches to prioritisation of conservation goals, and how nature reserves can be designed to improve conservation potential.

The aim of this module is to provide students with the opportunity to design and undertake a project from start to finish, which will involve working as part of a team and collecting individual and group data in an unbiased scientific manner. Students will develop the ability to distinguish effectively between variation due to robust effects and underlying uncontrolled variation, whilst statistically analysing and presenting their findings to the class in a suitable format.

By the end of the module, students will have the ability to critically appraise information and report the findings of their scientific endeavours to different audiences using a variety of methods, including scientific reports and PowerPoint presentations, in addition to developing a range of generic and specialist skills gained that will be useful in a competitive job market.

Students will be able to understand and integrate information from a variety of sources, whilst utilising skills of written critique of primary and secondary literature. They will also be developed in the ability to interrogate bibliographic databases and summarise pertinent information.

Vertebrates (including fish, amphibians, reptiles, birds and mammals) display a staggering diversity of shapes and sizes, and are adapted to a wide array of environments, from hot deserts to freezing oceans. The aim of this module is to introduce this broad range of forms and functions, putting physiological and behavioural processes firmly within a whole organism and evolutionary context.

This module will introduce students to the major vertebrate taxonomic groups: it will explore how they have evolved to exploit different environmental niches on land, in water and in flight; and how their anatomy, reproduction, thermoregulation, etc. have all become fine-tuned to cope with the challenges of their evolved lifestyle. Students will be able to apply their general knowledge of vertebrate biology to species-specific examples: comparing and contrasting different forms and functions; and critically evaluating hypotheses proposed in order to explain vertebrate diversity.

They will also gain more generic transferable skills such as critical discussion, application of knowledge to new situations, data analysis and report writing. Throughout the module, students will consider how form, function and strategy will impact the vulnerability of vertebrates to on-going environmental change.

The research project gives students first-hand experience of research and also the opportunity to be immersed in, and learn about, an area of work which is of current interest. Students plan, conduct and report on an open-ended investigation, often related to research interests of a member of staff. Projects cover a very wide variety of topics and may be carried out in a variety of ways. They involve a significant amount of original work and analysis to be carried out by students so that they gain experience in a range of skills, including experimental design and the testing of hypotheses. The results of the research are reported in an 8,000 word dissertation and an oral presentation.

In this module students will work together as a team to propose a solution to a problem of biological relevance, for example antibiotic resistance, invasive species or healthy ageing. The solution may be a patentable, commercial product or a policy proposal. Weekly workshop sessions will be held for the whole class which will include presentations from external speakers on topics such as intellectual property, project management and negotiating skills. Each team will choose a leader who will be responsible for organising regular meetings in which ideas are developed, tasks assigned and information gathered. The team will produce a report in the form of a patent application or policy document which will form part of the module assessment. The remainder of the assessment will be based on an oral presentation. Peer-assessment will be used to adjust tutors' marks according to individual contribution to the project.

This module explores how and why animals behave in the way that they do, building on many of the major themes of the Evolution module to highlight the links between behaviour, ecology and evolution. The central aim will be to understand the fitness consequences of behaviour - by focusing on three of the most important topics in behavioural research (reproduction, sociality and communication), we will investigate how the behaviour of an individual has evolved to maximise its survival and reproductive success.

Students will gain an understanding of how and why we study animal behaviour, at the same time developing their appreciation of scientific best practice. Students will be encouraged to relate specific knowledge to broader issues in ecology and evolution, and to critically reflect on what animal behaviour can tell us about behaviour in our own species. Additionally, students will be able to describe what behaviour actually is and understand the major factors that influence how animals (including humans) behave. Students will also develop the level of knowledge necessary to discuss a wide diversity of animal behaviours in a broad range of species, and describe the major approaches to understanding behaviour and apply Tinbergen's four questions to behavioural processes. Students will gain an enhanced understanding in a range of areas, including the importance of both nature and nurture in the evolution of behaviour, the ecological pressures that shape behaviour, the importance of the fitness consequences of behaviour at the individual level and the concepts of kin selection and inclusive fitness

For 50 years, thanks to evolutionary theory, we’ve known why we are fated to age and die, but our understanding of the mechanisms has been a lengthy evolution in itself. Only relatively recently, with the use of modern molecular biology tools, do we begin to understand the mechanistic basis of the ageing process, from early notions about rates of living to current ideas about modular yet interacting mechanisms including autophagy, protein synthesis, nutrient sensing, insulin-like signalling and disease resistance. Even now we do not clearly know what makes us age. Ageing is perhaps the most multidisciplinary area of study and is certainly one of the last great mysteries in biology.

This module introduces the area and the methodologies with which ageing is studied. Teaching is through lectures, workshops, practical work, individual and group-based coursework and private study.

In this module students are given an overview of the cellular and molecular processes that underpin the development of cancer. This will enable students to discuss the various factors that can affect cancer susceptibility. Students will look at the approaches taken to treat cancer, including some of the new generation of molecularly-targeted cancer therapies.

The ability of cells to communicate with one another using signalling pathways is of fundamental importance in multicellular organisms such as mammals. Cell signalling enables the transmission of information that is required for the correct co-ordination of metabolism, growth and development.

This module revises the basic principles of cellular communication, exploring the molecular basis of signalling in detail by using key signalling pathways as examples. The combination of Lectures and Workshops allows students to evaluate influential scientific discoveries, whilst Laboratory practicals provide the opportunity to put theory into practice.

This module explores some of the key roles played by ion channels and calcium ions in the communication that takes place within and between cells. The module is split into two linked themes. Firstly, an introduction to the diversity of ion channel families and their biological functions including the many different cellular processes throughout the life history of cells that are regulated by calcium ions as signals. Secondly, an investigation of the importance of ion channels and calcium signalling in animals, and human physiology in particular, using examples of diseases that are caused when ion channels malfunction (e.g. myotonia, malignant hyperthermia, sudden heart arrest caused by long QT syndrome.) or calcium signalling is disrupted (e.g. Alzheimer’s disease, polycystic kidney disease, pancreatitis). Students also gain hands-on experience of the techniques used to study ion channels and calcium signalling in cells.

Every day our body does something remarkable, but we are completely unaware of it most of the time: our immune system is constantly protecting us from pathogens in our environment as well as threats from within. This highly evolved, interdependent collection of organs, cells and chemical messengers is continually scanning our tissues for any unwanted intruders or abnormal cells. When we get ill, with a cold for example, full mobilisation of our immune system sends armies of cells and molecules to fight the problem in what can sometimes literally be a fight to the death. Fortunately for us, our immune system wins the battle almost every time!

In this module we examine the various components of the immune system – the organs, cells, and messengers, and how they function in health and illness. We look at particular threats such as allergies, infectious diseases and cancer, providing students with a good understanding of how this vital component of our bodies keeps us well.

Coral reefs are one of the most biodiverse ecosystems on Earth and have inspired the development of some of the most far-reaching theories in ecology. These ecosystems are distributed throughout the tropics and often dominate the shallow seas. They are also important for many millions of people worldwide yet are under increasing threat from climate change and more direct anthropogenic disturbance. This module aims to provide a solid grounding in coral reef biology, ecology and evolution, with a focus on corals and reef fishes, building on broad ecological principles laid down in previous years. Students will apply this understanding to evaluate threats and their potential solutions, developing an appreciation of the precarious nature of the most complex habitat in the oceans. Specifically, the students will explore how and where coral reefs have emerged through time and adapted to life in the oceans, the delicate balance of interactions that allow their enormous variety of species to coexist, and emerging threats and solutions to their continued existence.

The aim of this module is to illustrate some of the ways in which plants achieve this and to provide an insight into the physiological mechanisms that underlie plant ecology. Students will explore how plants respond to specific environmental cues and the ways in which they are able to adapt to a variety of stressful environments. All of these processes will be viewed from both an agricultural and an ecological perspective. Students will also gain an understanding of the environmental constraints on plant growth and productivity and an appreciation of the degree of plasticity and adaptability that plants display. They will develop an appreciation of the importance of a detailed understanding of these plant traits if we are to achieve the increases in crop productivity (through management or breeding) that will be required for food security in the face of global climate change.

This module will equip students with the ability to describe a range of features related to the subject, including the range of plant photomorphogenic and photoperiodic responses to light and their ecological significance, the response of plants and communities to high temperature and salinity, the rationale behind the use of deficit irrigation to increase water use efficiency , plant adaptations for efficient extraction of nutrients from the soil, the way in which leaves and roots function in drought-prone environments, and the regulation of growth of leaves and roots in drought-prone environments. Students will also develop the skill level required identify the practical applications of modifying plant responses to their light environment, discussing the problems posed by a hot dry climate for plant growth and functioning and the rationale for breeding/engineering plants for increased water use efficiency, in addition to gaining the necessary understanding of the cellular and whole plant tissue basis of plant drought resistance and the physiological basis of salt tolerance.

Research and practice in biomedicine continues to evolve more rapidly than at any other time in history, raising fascinating but complex moral and ethical challenges for those studying and working in the field. Understanding ethics in biomedicine and the relationship between science and society has become an essential element in biomedical degree training.

This module builds on the Biomedicine and Society module, aiming to help students develop a deeper understanding of key ethical principles used in biomedicine and some major cultural, social and political influences that define research agendas and fuel ethical debates in the public perception of biomedicine.

The module takes on a seminar format structured around three core themes:

• The development of ethical principles in biomedicine
• Ethical practice and current debates in animal and human research including clinical trials
• Ethical challenges such as those emerging in genetics and regenerative medicine and how these are debated in the media.

How is DNA, the fundamental building block of life, organised and expressed in different types of organisms such as bacteria and humans? Lectures comparing eukaryotic and prokaryotic gene organisation and expression, chromatin structure and DNA repair will seek to answer this question. In addition, students will study the application of genetics to science and technology during practical and workshop sessions, providing them with the opportunity to develop group and independent working skills whilst reinforcing theoretic concepts.

Plants and animals in their natural environments interact with a wide range of other living organisms. These include both beneficial interactions and damaging encounters with parasites, pathogens and herbivores. The module examines the different kinds of organisms that have evolved a parasitic lifestyle and the ways in which they parasitize their hosts. In parallel, the module will introduce the different strategies that plants and animals use to defend themselves, including the recruitment of other organisms to act as allies. The continuing conflict between hosts and parasites results in a so-called 'evolutionary arms race'.

Practical work will develop laboratory skills, and assessment will develop skills in data analysis, writing and argument. The module will also examine the evolutionary costs and benefits of defence, and the evidence for short and long-term immunological memory. Since the module is aimed primarily at addressing ecological and physiological questions rather than the biomedical aspects of parasitology, the focus will be on invertebrate rather than vertebrate hosts.

Students will be able to describe a range of subject specific topics, such as the main groups of parasitic organisms and their lifestyles; the structural and behavioural defences against parasites, pathogens and herbivores in plants and animals, and the key features of innate and adaptive immunity in plants and animals. This module will also enhance students’ ability to identify the main selective processes shaping the evolution of host resistance to parasites, along with providing explanations as to why many defence mechanisms are inducible rather than permanently expressed, and how specialist herbivores and parasites have co-evolved with their hosts to overcome resistance.

In this module, students will be shown how, through manipulation of species, communities and ecosystems, habitats can be managed in a sustainable way that preserves and enhances their aesthetic, scientific, recreational, and often utilitarian, value. The creation of new habitats will be considered, as well as management of existing areas of conservation interest. The module is largely taught by external lecturers who are directly involved in the application of ecological principles to practical problems.

Students will develop the level of ability required to describe the nature of selected habitat types, as well as explaining a series of underlying ecological processes which necessitate management. Students will also be able to identify the techniques used for conservation management specific to a range of habitat types, in addition to reinforcing a range of transferrable skills, such as the ability to present scientific data clearly and concisely, in both written and oral format. Students will learn to work autonomously as well as being involved in group work.

Join a discussion and debate where you are encouraged to critically examine primary literature and ideas on topical issues in conservation biology in the UK and globally. Gain an understanding of the key factors that constrain conservation and of the interdisciplinary nature of conservation problems in the real world.

This module aims to provide an understanding of the organisation of the human genome, how disease genes are mapped and how mutations are identified leading to the development of diagnostic tests. The impacts of massively parallel next generation DNA sequencing, microarrays and SNP genotyping on gene discovery and disease diagnosis are examined. The application of modern genetic techniques to identifying susceptibility genes for complex, multifactorial traits will also be studied. A range of diseases will be examined in detail both in lectures and in case study workshop sessions. The final lecture looks at gene therapy and considers the future for treatment of genetic disorders. The practical session aims to give students an opportunity to study their own DNA in a forensics scenario, using techniques that are widely applicable in modern molecular genetics.

Students will be introduced to the importance of molecular, metabolic and cellular interactions within parasitic protists, and between a range of parasitic protists and their hosts.

The course will provide students with an understanding of how the life cycle strategies used by protists enable them to gain access to, and survive within, the host as well as the impact that protist parasites have on human health. Practicals will provide an opportunity for students to apply immunological skills to investigate the host-parasite interaction.

Nervous system function, from formation in the embryo to sensory systems and the neural control of complex behaviours, is the focus of this module. The emphasis is on model systems and the use of genetic tools to elucidate developmental pathways and neural circuits. Practical exercises are used to illustrate some of the functions of nervous systems and how these can be manipulated by genetic intervention.

Students are encouraged to access and evaluate information from a variety of sources and to communicate the principles in a way that is well-organised, topical, and recognises the limits of current hypotheses. On completion of the module, students will be equipped with practical techniques including data collection, analysis and interpretation.

Microbiology for the biomedical scientist comprises screening samples to identify and assess microbiological pathogens that cause disease and, enable front line medical staff to choose the correct therapy for successful eradication of the infection. Increasing numbers of these infections are community acquired and many are contracted from, or in, the environment. The environment therefore plays an increasing role in the life cycle and ecology of many pathogens. This in turn, is having an increasing impact on human health and national health services. The increase is a combination of changing environmental conditions (such as land use changes, global warming) and an ever evolving microbial community, most of which do not harm but a few can cause mild to fatal diseases when the opportunity arises. Also cycling in the environment are obligate pathogens which will cause infections if contracted. Furthermore, there are new diseases emerging (e.g. Ebola) and others thought to have been controlled are now re-emerging such as cholera. Using specific microbial pathogens as examples, this module examines the factors and interactions that allow microbial infections to be transmitted from the environment to humans and how their life cycle plays an important role in their emergence, persistence, transmission and infection. It also examines antibiotic resistance: how it has emerged, the different types of resistance, its management and the complications that it imposes on the treatment of these diseases.

Assessment:

1. Exam: 2 hour paper with two questions in sections A and B. Students are required to answer one question from each.

2. Coursework is an extended essay of 2000 words based on the lectures and field trip. The title will be announced in the first lecture.

Understanding how life works depends to a great extent on understanding how proteins work. Thanks to the Human Genome Project, we now have a catalogue of all the proteins that are encoded in the human genome. This might be thought of as life’s toolbox. The next questions are: how do those tools work; how do they interact with each other; and how have they evolved over the billions of years of evolutionary time that have led to us? This module introduces modern techniques for the study of protein structure, function and evolution.

Lectures cover: structural-functional relationships in proteins; methods for detecting the action of Darwinian selection in protein evolution; methods for reconstructing the evolutionary events that have led to present-day proteins; and, the new lab techniques that are allowing us to study protein function on a large scale. In the practical sessions, students will gain hands-on experience of molecular phylogenetics – the main tool for studying evolution at the molecular level – as it is applied to proteins. Assessment is by an exam and a coursework essay on a protein of your choice, giving students a chance to apply their new knowledge of protein biochemistry to any of their own areas of interest in biology.

In this module, students will be shown how, through manipulation of species, communities and ecosystems, habitats can be managed in a sustainable way that preserves and enhances their aesthetic, scientific, recreational, and often utilitarian, value. The creation of new habitats will be considered, as well as management of existing areas of conservation interest. The module is largely taught by external lecturers who are directly involved in the application of ecological principles to practical problems.

Students will develop the level of ability required to describe the nature of selected habitat types, as well as explaining a series of underlying ecological processes which necessitate management. Students will also be able to identify the techniques used for conservation management specific to a range of habitat types, in addition to reinforcing a range of transferrable skills, such as the ability to present scientific data clearly and concisely, in both written and oral format. Students will learn to work autonomously as well as being involved in group work.

Modern resource-intensive agriculture has proved incredibly successful in delivering relatively abundant, cheap food (at least in the developed world), but sometimes at considerable environmental cost. Therefore the general public is usually keen to embrace "sustainable agriculture" but is generally unaware of the economic and food production costs of proposed changes in crop management. By emphasising the concept of crop resource use efficiency, this module focuses on the viability of less intensive agricultural systems.

Students will critically examine primary literature on topical issues concerning the sustainability of different agricultural systems. They will gain an understanding of the key factors constraining food production, and the environmental and food production consequences of different crop production systems.

In addition to gaining the ability to identify key issues affecting the sustainability of agriculture, students will critically appraise the literature on these issues, and will develop the skillset required to recognise the economic and societal problems constraining the adoption of more environmentally sustainable agriculture. Ultimately, students will gain the ability to discuss alternative scenarios and solutions for key environmental problems associated with agriculture and document said issues in a cogent and critical manner.

During this residential field course, based in Kenya, students will be given an overview of tropical ecology via a series of lectures, field exercises, workshops and debates, using the geographic, abiotic and biotic characteristics of the Rift Valley, East Africa: from aquatic ecosystems to arid savannah. They will experience ecological processes, biodiversity and conservations issues commonplace within the tropics.

Throughout the field course, students will design and conduct surveys for the following:

• Birds - timed counts, transects and / or mist netting will be conducted at various sites and in different habitats at particular sites eg protected grassland plots versus goat grazed scrub
• Aquatic invertebrates and fish – net versus trap strategies
• Camera-trapping – grids, baited versus non-baited, targeting of specific organisms
• Light trapping – position, duration, assessing catch

Students will gain a direct appreciation of the issues, problems and solutions surrounding wildlife and human conflicts at a variety of scales.

Together with BIOL469 MSci Research Project, the projects comprise half of the final year assessment for MSci schemes. The literature review provides the opportunity for students to explore an area of bioscience, related to the research project, in depth. Published articles are summarised and critically reviewed to identify gaps in current knowledge and to provide the background for the student’s own research. The literature review consists of a 4,000 word dissertation which is written during the autumn term of the final year and submitted along with the research project in the summer term.

Together with BIOL470 MSci Project Literature Review, the projects comprise half of the final year assessment for MSci schemes. The research project allows students to spend an extended period of time in the research lab of a member of academic staff, carrying out original research and working alongside PhD students and other researchers. Students develop skills learned in the third year project to enhance student independence and provide experience of the laboratory based research environment. Students develop an adaptable, flexible, and effective approach to research questions and the ways in which their practical skills can be used to address such questions. Results of the research are reported in an 8,000 word dissertation submitted during the summer term of the final year.

Module convenor

• Dr Derek Gatherer

Timetable

• Week 17–18

Aims and scope

• This module aims to encourage students to access and evaluate information from a variety of sources and to communicate the principles in a way that is well-organised, topical and recognises the limits of current hypotheses. It also aims to equip students with practical techniques including data collection, analysis and interpretation.

Learning Outcomes

On successful completion of this module, students will be able to:

• Work effectively to produce a knowledgeable report
• Interpret data and design bioinformatics “experiments” (meaning planned sequences of computer analyses designed to shed light on a scientific problem)
• Perform a standard repertoire of bioinformatics skills
• Be able to describe the uses and limitations of the various ’omic technologies
• Be able to critically evaluate papers in the fields of bioinformatics
• Be able to understand and discuss topics in bioinformatics

Assessment

• Compulsory Exam 50%
• Compulsory Coursework 50%

Recommended reading

• Michael Agostino. Practical Bioinformatics. Garland Science. ISBN 978-0-8153-4456-8 Arthur M Lesk.
• Introduction to Bioinformatics 4th ed. Oxford Univ Press ISBN 978-0-19-965156-6
• Carl Zimmer & Douglas Emlen. Evolution. Making Sense of Life Roberts and Co. ISBN 978-1-93-622117-2
• AD Baxevanis & BFF Ouellette Bioinformatics 3rd ed. Wiley ISBN 0-471-47878-4
• Paul H Dear (ed) Bioinformatics. Scion ISBN 978-1-90-484216-330
• Masatoshi Nei & Sudhir Kumar Molecular evolution and phylogenetics (Also available on http://lib.myilibrary.com/Open.aspx?id=83437)
• Drummond AJ & and Bouckaert RR. Bayesian Evolutionary Analysis with BEAST. Cambridge University Press ISBN 978-1107019652

This module focuses on key challenges facing the conservation of biodiversity today. We examine trade-offs between conservation goals and human desires, and wellbeing. The module highlights emerging understanding of the complex relationships between biodiversity, ecosystem services and human life.

Students will be engaged with specific examples of how conservation science is changing to address social-economic-ecological conflicts. They are encouraged to critically analyse literature on topical issues confronting biodiversity conservation. By doing so, they will gain an understanding of the factors that constrain conservation aims, and of the need for interdisciplinary approaches to conserve biodiversity in the real world.

Those who take this module will develop an understanding of how conservation has changed, and be able to define criteria to identify species and ecosystems of high conservation importance. They will also learn how conflicts between social, economic and ecological objectives can be understood and addressed in partnerships.

This module introduces the concept of protein misfolding disorders, and expands this through consideration of two major neurodegenerative diseases; Alzheimer’s disease and Parkinson’s disease. The role of oxidative stress and proteases in neurodegenerative diseases is covered in detail, before examining the role of lipids in various brain disorders. The module also considers how animal models can be used to study both normal brain aging and neurodegenerative diseases.

The aim of this module is to provide a broad understanding of the human immune system, more detailed knowledge of human immunological disorders and the application of cutting edge immunological research to biomedical science and clinical practice. Technical skills associated with this course include experience and data analysis of advanced flow cytometry techniques and insight into how research findings are reported and presented to the scientific community and media.

The focus is to understand the component parts and the interdisciplinary basis of the global food system. To this end, students will examine challenges facing global agricultural production as a result of climate change. They will also gain an understanding of the shortage of key resources for food production and the subsequent issues that affect people’s access to food.

In addition to this, the module will demonstrate how basic plant physiology can inform both plant breeding and agronomy to increase the sustainability of agriculture. The factors impacting food safety and food quality (especially nutritive value) will also be explored.

Ultimately, students will develop a familiarity with several current/impending crises in global food security.

Students will learn about the planning that goes into, and the ecological principles underlying, habitat management.

There will be a series of excursions to sites of conservation interest, led by external contributors and experts within the Department. Workshops will train students in habitat management techniques and planning, and students will write a conservation management plan for a particular site.

Students will be able to describe how the principles underlying the management of habitats for conservation can be applied in a range of habitat types, and will be able to construct a standard conservation management plan.

They will also develop skills in identifying, abstracting and synthesising information, and report writing.

Students will be given an introduction to the foundations of lake ecology, an area with an acknowledged national lack of expertise. The module presents a holistic approach to the drivers and internal interactions that control water quality in lakes.

Those who take this module will be taught basic ecological principles, which will be elucidated using lake ecology. They will also be introduced to the various applications of state-of-the-art techniques and provided with essential background information for dealing with regulation such as the Water Framework Directive.

This module also includes a field trip and practicals that will give students experience of working with the Centre for Ecology & Hydrology in a management/policy context. Modelling to predict impact of management measures is also an important aspect of the module, and an appreciation of its principles and uses when it comes to lakes and catchment will be encouraged.

Students will come to understand the state-of-the-art tools and approaches needed to study and manage lakes as used in industry, government and science.

This module aims to provide students with a broad understanding of a range of pathogens and their impact on human health, and to understand how the human body responds to these challenges. Students are also introduced to the new challenges faced by healthcare systems including emerging/re-emerging infectious diseases and antibiotic resistance and so develop an awareness of the challenges and realities of controlling infectious diseases. Students also develop an appreciation of the role of epidemiological and mathematical modelling in predicting and controlling pathogenic organisms.

The aim of this module is to provide students with a broad understanding of the different types of model systems used in research on human diseases, an appreciation of the advantages and disadvantages of each model, and an awareness of some major discoveries that have been made using these disease models.

This module provides insight into the underlying molecular events in the development of cancer, how cancers spread through the body and explain how an understanding of the molecular basis of cancer has led to the development of novel cancer treatments. Workshops allow students to study the aetiology and progression of one particular type of cancer in depth, and also to understand how cancer is studied in practice.

Students will gain knowledge of identification, sampling and monitoring methods for some key taxa and an understanding of how these methods may be used in a wider context, e.g. local, national and international contexts of different types of survey.

The module will have five sections, each delivered with one or two lectures and including a field component on campus or away. It will also include the analysis of quantitative data.

Those who take this module will be taught to identify some taxonomic groups to appropriate levels (species, genus, etc.) and will devise appropriate sampling regimes to derive population estimates or indices for population monitoring. They will also use other monitoring techniques that may be appropriate for recording behaviour and quantifying biodiversity.