Neural circuits linking frontal areas of the brain with the sub-cortical area called the corpus striatum in the basal ganglia. This frontal-striatal circuitry can be roughly compartmentalised into cognitive, limbic and motor projections. More specifically: the dorsolateral prefrontal circuit (preparation to respond), the anterior cingulate circuit (generation of motivation) and the orbitofrontal circuit (emotional and limbic integration). Impairments of executive functions and impulsivity are evident when the circuitry is disrupted. Also, involved in attention-deficit/hyperactivity disorder (ADHD), Huntington’s disease, obsessive-compulsive disorder and Tourette’s syndrome.
See Attention-deficit/hyperactivity disorder (ADHD), Basal ganglia (anatomy), Executive function (EF), Huntington’s disease (or chorea), Impulsivity, Limbic system, Obsessive-compulsive disorder, Tourette’s syndrome