{"id":7187,"date":"2019-05-22T15:54:09","date_gmt":"2019-05-22T15:54:09","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/bungarotoxin_-btx\/"},"modified":"2019-05-22T15:54:09","modified_gmt":"2019-05-22T15:54:09","slug":"bungarotoxin_-btx","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/bungarotoxin_-btx\/","title":{"rendered":"\u03b1-bungarotoxin (\u03b1-BTX)"},"content":{"rendered":"<p>A 74 amino-acid substance that presynaptically blocks neuromuscular transmission. &nbsp;It is one of the so-called curare mimetic&nbsp;\u03b1-neurotoxins, which are among the most lethal constituents of venom in the snake <a href=\"http:\/\/www.snakesoftaiwan.com\/Bungarus%20multicinctus\/species_bungarus_multicinctus.htm\" target=\"_self\" data-editable-link=\"http:\/\/www.snakesoftaiwan.com\/Bungarus%20multicinctus\/species_bungarus_multicinctus.htm&amp;target=_self\" rel=\"noopener noreferrer\">Bungarus multicinctus<\/a>. &nbsp;These toxins bind with very high affinities and selectivities to the nicotinic acetylcholine receptor (AcChoR), and in doing so block neuromuscular transmission through preventing the depolarising action on postsynaptic membranes.<\/p>\n<p>See <a href=\"acetylcholine_-ach-\">Acetylcholine (AcH)<\/a>, Akinesis, <a href=\"amino_acids\">Amino acids<\/a>, Botulinus (or botulinum or botox).<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A 74 amino-acid substance that presynaptically blocks neuromuscular transmission. &nbsp;It is one of the so-called curare mimetic&nbsp;\u03b1-neurotoxins, which are among the most lethal constituents of venom in the snake Bungarus multicinctus. &nbsp;These toxins bind with very high affinities and selectivities to the nicotinic acetylcholine receptor (AcChoR), and in doing so block neuromuscular transmission through preventing &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/bungarotoxin_-btx\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;\u03b1-bungarotoxin (\u03b1-BTX)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7187","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7187","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7187"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7187\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7187"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7187"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7187"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}