{"id":7226,"date":"2019-05-22T15:54:34","date_gmt":"2019-05-22T15:54:34","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/adhesion_molecules\/"},"modified":"2019-05-22T15:54:34","modified_gmt":"2019-05-22T15:54:34","slug":"adhesion_molecules","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/adhesion_molecules\/","title":{"rendered":"Adhesion molecules"},"content":{"rendered":"<p>Involved in forming contacts between cells (focal contacts) and between them and the extracellular matrix. &nbsp;Several families of such molecules have been identified by <a href=\"http:\/\/www.webofstories.com\/play\/15740\" class=\"cc-route-enabled\" data-editable-link=\"http:\/\/www.webofstories.com\/play\/15740&amp;target=_self\" target=\"_self\" rel=\"noopener noreferrer\">Gerald M. Edelman<\/a> and colleagues, among others. &nbsp;Cell-cell adhesion molecules (CAMS) can be either calcium dependent or independent, the former including cadherins, inter grins and selections, and which appear to be important in tissue-specific cell-cell adhesion during vertebrate embryogenesis (e.g., in the binding of blastomeres). &nbsp;Calcium independent CAMS include immunogloblin-like proteins termed neural cell adhesion molecules (N-CAMs), which are important in determining the shapes of cells. &nbsp;Most integrins appear to bind cells to their extracelluar matrix, and are also present in the growth cones of axons where they play a role in the guidance of axons during their migration and growth.<\/p>\n<p>See <a href=\"axon_pathway_selection\">Axon pathway selection<\/a>, <a href=\"blastomere\">Blastomere<\/a>, <a href=\"blastula\">Blastula<\/a>, <a href=\"cadherins\">Cadherins<\/a>, <a href=\"cell_adhesion_molecules_-cams-\">Cell adhesion molecules (CAMs)<\/a>, <a href=\"cell_locomotion\">Cell locomotion<\/a>, <a href=\"embryogenesis\">Embryogenesis<\/a>, <a href=\"extracellular_matrix\">Extracellular matrix<\/a>, <a href=\"growth_cone\">Growth cone<\/a>, <a href=\"integrins\">Integrins<\/a>, <a href=\"neural_cell_adhesion_molecule_-n-cam-\">Neural cell adhesion molecule (N-CAM)<\/a>, Oligpsaccharides, Peripheral nervous system (PNS)<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Involved in forming contacts between cells (focal contacts) and between them and the extracellular matrix. &nbsp;Several families of such molecules have been identified by Gerald M. Edelman and colleagues, among others. &nbsp;Cell-cell adhesion molecules (CAMS) can be either calcium dependent or independent, the former including cadherins, inter grins and selections, and which appear to be &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/adhesion_molecules\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Adhesion molecules&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7226","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7226"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7226\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7226"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}