{"id":7289,"date":"2019-05-22T15:55:16","date_gmt":"2019-05-22T15:55:16","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/apical_ectodermal_ridge_-aer\/"},"modified":"2019-05-22T15:55:16","modified_gmt":"2019-05-22T15:55:16","slug":"apical_ectodermal_ridge_-aer","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/apical_ectodermal_ridge_-aer\/","title":{"rendered":"Apical ectodermal ridge (AER)"},"content":{"rendered":"<p>The layer of transient surfaceectodermal cells at the apex of the embryonic limb bud (see figure below). &nbsp;Considered to exert an inductive influence on the condensation of underlying mesenchyme, and thereby to stimulate elongation of the limb along the proximal-distal axis and maintain signals required for patterning the limb. &nbsp;The majority of cell division (mitosis) occurs just deep to AER, and this region is known as the progress zone.<\/p>\n<\/p>\n<p><img decoding=\"async\" src=\"..\/wp-content\/uploads\/2019\/05\/ApicalEctodermalRidge.png\" \/><\/div>\n<\/div>\n<p class=\"\" style=\"text-align: center; \">Ectodermal cells making up the ridge on the chick limb bud<\/p>\n<p class=\"\" style=\"text-align: left;\">See Ectoderm, Induction (embryology), Limb bud, &nbsp;Mesenchyme, Mitosis, Progress zone<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The layer of transient surfaceectodermal cells at the apex of the embryonic limb bud (see figure below). &nbsp;Considered to exert an inductive influence on the condensation of underlying mesenchyme, and thereby to stimulate elongation of the limb along the proximal-distal axis and maintain signals required for patterning the limb. &nbsp;The majority of cell division (mitosis) &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/apical_ectodermal_ridge_-aer\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Apical ectodermal ridge (AER)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7289","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7289"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7289\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7289"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7289"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}