{"id":7409,"date":"2019-05-22T15:56:34","date_gmt":"2019-05-22T15:56:34","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/brain_damage_studies\/"},"modified":"2019-05-22T15:56:34","modified_gmt":"2019-05-22T15:56:34","slug":"brain_damage_studies","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/brain_damage_studies\/","title":{"rendered":"Brain damage studies"},"content":{"rendered":"<\/p>\n<p>Used to help determine the functions of parts of the brain; a person with damage to a specific brain area often shows deficits in specific abilities (e.g., damage to the hippocampus leads to deficits in memory). &nbsp;One of the salient features of such studies in recent times has been an interest the neuroprotective factors of hormones. &nbsp;One such hormone is <a href=\"http:\/\/www.merriam-webster.com\/medical\/ghrelin\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.merriam-webster.com\/medical\/ghrelin&amp;target=_self\" rel=\"noopener noreferrer\">ghrelin<\/a>, which has been suggested it protects, for example, against neuronal damage induced by glucose-oxygen deprivation in the hypothalamus and cortex, and neurons in the hippocampus and cortex against cerebral ischemia. &nbsp;Functional deficits are not always a consequence of (acquired) brain damage as the case of <a href=\"https:\/\/www.facebook.com\/jason.padgett.39\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"https:\/\/www.facebook.com\/jason.padgett.39&amp;target=_self\" rel=\"noopener noreferrer\">Jason Padget<\/a>t demonstrates. &nbsp;He was subjected to a mugging that involved being knocked to the ground and kicked repeatedly in the head. &nbsp;After recovering from concussion, his perception of the world changed dramatically, manifesting synesthesia: he now saw the world (e.g., the flow of water) in terms of fractal dimensions. &nbsp;He was invited to Finland for a session of brain-imaging under the direction of the neuroscientist <a href=\"http:\/\/www.umsl.edu\/~philo\/People\/Faculty\/facultybios\/brogaard.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.umsl.edu\/~philo\/People\/Faculty\/facultybios\/brogaard.html&amp;target=_self\" rel=\"noopener noreferrer\">Berit Brogaard<\/a>. &nbsp;In a series of <a href=\"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/.U3OvcShEAyU\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/.U3OvcShEAyU&amp;target=_self\" rel=\"noopener noreferrer\">functional magnetic resonance imaging recordings<\/a>, Padgett&#8217;s left parietal and frontal areas became active when he was subjected to mathematical formulae and that gave rise to synesthetic fractals, but bilateral activation when exposed to nonsense formulae. &nbsp;Subsequent transcranial magnetic stimulation (TMS) deprived him of these experiences. &nbsp;What this case study suggests is that synesthetic imagery is generated by cortical areas not typically involved in visual imagery. &nbsp;As he describes in his book <a href=\"http:\/\/www.struckbygenius.com\/\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.struckbygenius.com\/&amp;target=_self\" rel=\"noopener noreferrer\"><span class=\"\" style=\"font-style: italic;\">Struck by genius<\/span><\/a> (2014), written together with <a href=\"https:\/\/www.youtube.com\/watch?v=V4Qyahgl0uw\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"https:\/\/www.youtube.com\/watch?v=V4Qyahgl0uw?target=_self\" rel=\"noopener noreferrer\">Maureen Seaberg<\/a>, these &#8216;idiot savant&#8217;-like capacities came at a cost: post-traumatic syndrome disorder, obsessive-compulsive disorder, and social anxiety. &nbsp;His remarkable story has led to the claim the <a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304394012003618\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304394012003618&amp;target=_self\" rel=\"noopener noreferrer\">application of TMS<\/a> can temporarily boost creativity and memory. &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/p>\n<p>See <a href=\"basal_ganglia_-disorders-\">Basal ganglia (disorders)<\/a>, <a href=\"cerebellum_-disorders-\">Cerebellum (disorders)<\/a>, <a href=\"cerebral_cortex_-or_pallium-\">Cerebral cortex (or pallium)<\/a>, <a href=\"cerebral_cortex_-disorders-\">Cerebral cortex (disorders)<\/a>, <a href=\"double_dissociation\">Double dissociation<\/a>, <a href=\"fractals\">Fractals<\/a>, <a href=\"frontal_cortex\">Frontal cortex<\/a>, <a href=\"functional_magnetic_resonance_imaging_-fmri-\">Functional magnetic resonance imaging (fMRI)<\/a>, <a href=\"hippocampus\">Hippocampus<\/a>, <a href=\"hormones\">Hormones<\/a>, <a href=\"hypothalamus\">Hypothalamus<\/a>, <a href=\"ischemia\">Ischemia<\/a>, <a href=\"methyl_mercury\">Methyl mercury<\/a>, <a href=\"obsessive-compulsive_disorder_-ocd-\">Obsessive-compulsive disorder (OCD)<\/a>, <a href=\"parietal_cortex\">Parietal cortex<\/a>, <a href=\"synesthesia\">Synesthesia<\/a>, <a href=\"transcranial_magnetic_stimulation_-tms-\">Transcranial magnetic stimulation (TMS)<\/a><\/p>\n<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Used to help determine the functions of parts of the brain; a person with damage to a specific brain area often shows deficits in specific abilities (e.g., damage to the hippocampus leads to deficits in memory). &nbsp;One of the salient features of such studies in recent times has been an interest the neuroprotective factors of &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/brain_damage_studies\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Brain damage studies&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7409","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7409","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7409"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7409\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}