{"id":7424,"date":"2019-05-22T15:56:43","date_gmt":"2019-05-22T15:56:43","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/canalization\/"},"modified":"2019-05-22T15:56:43","modified_gmt":"2019-05-22T15:56:43","slug":"canalization","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/canalization\/","title":{"rendered":"Canalization"},"content":{"rendered":"<p>According to <a href=\"http:\/\/www.encyclopedia.com\/doc\/1G2-2830906186.html\" target=\"_self\" data-editable-link=\"http:\/\/www.encyclopedia.com\/doc\/1G2-2830906186.html&amp;target=_self\" rel=\"noopener noreferrer\">Conrad H. Waddington (1905-1975)<\/a>, this concept represents a general summary of a number of facts in genetics and embryology. &nbsp;Broadly speaking, it can be defined as the capacity of the epigenetic system to attain developmental end-states despite minor variations in initial conditions and conditions met during subsequent development (viz., genetic and environmental perturbations). &nbsp;The depth to which a developmental pathway is canalised or buffered is taken to represent the strength of its homeorhetic properties.<\/p>\n<p>See <a href=\"constraint\">Constraint<\/a>, <a href=\"determination\">Determination<\/a>, <a href=\"equifinality\">Equifinality<\/a>, <a href=\"epigenetic_landscape\">Epigenetic landscape<\/a>, <a href=\"epigenetics\">Epigenetics<\/a>, Homeorhesis<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to Conrad H. Waddington (1905-1975), this concept represents a general summary of a number of facts in genetics and embryology. &nbsp;Broadly speaking, it can be defined as the capacity of the epigenetic system to attain developmental end-states despite minor variations in initial conditions and conditions met during subsequent development (viz., genetic and environmental perturbations). &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/canalization\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Canalization&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7424","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7424","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7424"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7424\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}