{"id":7427,"date":"2019-05-22T15:56:45","date_gmt":"2019-05-22T15:56:45","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/carboxyhemoglobin_-cohb\/"},"modified":"2019-05-22T15:56:45","modified_gmt":"2019-05-22T15:56:45","slug":"carboxyhemoglobin_-cohb","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/carboxyhemoglobin_-cohb\/","title":{"rendered":"Carboxyhemoglobin (CoHb)"},"content":{"rendered":"<p>A derivative of haemoglobin, also known as carbon monoxide hemoglobin, it is a fairly stable union of carbon monoxide with haemoglobin instead of oxygen or carbon dioxide. &nbsp;It has a much higher affinity for hemoglobin than oxygen, and at high levels impairs the normal transport of oxygen by the blood. &nbsp;The normal value of CoHb in blood is 3%, but it can get as high as 15% in smokers. &nbsp;Levels change significantly, both in the mother and fetes during maternal smoking, and may lead to chronic intrauterine hypoxia and reduced birthweight. &nbsp;However, it is still not clear if the physiological effects of maternal smoking on fatal growth are due to decreased availability of oxygen as a consequence of the formation of COHb, or to the vasoconstrictive properties of nicotine.<\/p>\n<p>See <a href=\"hemoglobin\">Hemoglobin<\/a>, Hypoxia, <a href=\"intrauterine_growth_restriction_or_retardation_-iu\">Intrauterine growth restriction or retardation (IUGR)<\/a>, <a href=\"nicotine\">Nicotine<\/a>, Vasoconstriction<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A derivative of haemoglobin, also known as carbon monoxide hemoglobin, it is a fairly stable union of carbon monoxide with haemoglobin instead of oxygen or carbon dioxide. &nbsp;It has a much higher affinity for hemoglobin than oxygen, and at high levels impairs the normal transport of oxygen by the blood. &nbsp;The normal value of CoHb &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/carboxyhemoglobin_-cohb\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Carboxyhemoglobin (CoHb)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7427","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7427"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7427\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}