{"id":7890,"date":"2019-05-22T16:01:45","date_gmt":"2019-05-22T16:01:45","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/estradiol\/"},"modified":"2019-05-22T16:01:45","modified_gmt":"2019-05-22T16:01:45","slug":"estradiol","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/estradiol\/","title":{"rendered":"Estradiol"},"content":{"rendered":"<\/p>\n<p>The main oestrogen in humans, it is a steroid (or sex) hormone produced by <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC333134\/pdf\/jcinvest00642-0209.pdf\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC333134\/pdf\/jcinvest00642-0209.pdf&amp;target=_self\" rel=\"noopener noreferrer\">aromatization<\/a> of testosterone (i.e., the transformation of testosterone into estradiol). &nbsp;It acts on oestrogen receptors throughout the body, with the largest amounts of estradiol being produced by the granulosa cells of the ovaries. &nbsp;Essential for sexual functioning, it also supports bone growth in terms of strength and density. &nbsp;While labeled the &#8216;female hormone&#8217;, smaller amounts, however, are derived from testicular and adrenal testosterone. &nbsp;In men, aromatization has been implicated in the exacerbation of prostate hypertrophy and and increased risk of cancer due to elevated levels of estrogen.&nbsp;<\/p>\n<p>See <a href=\"adolescent_growth_spurt\">Adolescent growth spurt<\/a>, <a href=\"estrogen\">Estrogen<\/a>, <a href=\"hormones\">Hormones<\/a>, <a href=\"menarche\">Menarche<\/a>, <a href=\"puberty\">Puberty<\/a>, <a href=\"steroid_hormones\">Steroid hormones<\/a>, Testosterone <\/p>\n<\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The main oestrogen in humans, it is a steroid (or sex) hormone produced by aromatization of testosterone (i.e., the transformation of testosterone into estradiol). &nbsp;It acts on oestrogen receptors throughout the body, with the largest amounts of estradiol being produced by the granulosa cells of the ovaries. &nbsp;Essential for sexual functioning, it also supports bone &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/estradiol\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Estradiol&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7890","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7890","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7890"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7890\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7890"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7890"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7890"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}