{"id":7929,"date":"2019-05-22T16:02:11","date_gmt":"2019-05-22T16:02:11","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/extrapyramidal_system\/"},"modified":"2019-05-22T16:02:11","modified_gmt":"2019-05-22T16:02:11","slug":"extrapyramidal_system","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/extrapyramidal_system\/","title":{"rendered":"Extrapyramidal system"},"content":{"rendered":"<p>The phylogenetically older one of two pyramidal systems that originate in the motor cortex, the other being the pyramidal system (or corticospinal tract). &nbsp;Together, they are responsible for the control and coordination of voluntary movements, as well as the maintenance of balance and posture. &nbsp;Thus, they are not functionally independent of each other, and interact at all levels of the nervous system. &nbsp;Moreover, both systems should be considered as functional rather than anatomical units. &nbsp;The extrapyramidal system serves to refine voluntary movements and postural control as well. &nbsp;Its constituent parts, in addition to the cerebellum, are the basal ganglia the red nucleus, and the reticular formation, the reason why it is labeled &#8216;extra&#8217; as it involves structures outside the pyramidal system (see figure below). &nbsp;All these structures send excitatory or inhibitory information to the so-called lower motoneurons (i.e., anterior horn cells) in the spinal cord via muti-synaptic, and thus, indirect pathways. &nbsp;In this way, it is different from the pyramidal system that forms monosynaptic connections in the spinal cord. &nbsp;Lesions to the extrapyramidal system result in various sorts of dyskinesias and degenerative diseases such as Parkinson&#8217;s disease.&nbsp;<\/p>\n<p class=\"\" style=\"text-align: center;\">\n<p><img decoding=\"async\" src=\"..\/wp-content\/uploads\/2019\/05\/image039x.png\" \/><\/div>\n<\/div>\n<p class=\"\" style=\"text-align: center;\">Extrapyramidal system:&nbsp;starting in the premotor cortex, it relays information to the basal ganglia where it passes through the caudate nucleus, putamen (both inhibitory), the excitatory globus pallid us I (GPI) and II (GPII), the sub-thalamic nuclei, substantial nigra to the red nucleus, and from here to the spinal cord. The thalamus and the hypothalamus provide additional inputs to the system.&nbsp;<\/p>\n<p>See <a href=\"basal_ganglia_-anatomy-\">Basal ganglia (anatomy)<\/a>, <a href=\"cerebellum_-anatomy-\">Cerebellum (anatomy)<\/a>, <a href=\"cerebellum_-functions-\">Cerebellum (functions)<\/a>, <a href=\"corticospinal_tracts_-cst-\">Corticospinal tracts (CST)<\/a>, Direct corticospinal connections (or tracts), Corticospinal tract (CST), <a href=\"dyskinesia\">Dyskinesia<\/a>, <a href=\"hypothalamus\">Hypothalamus<\/a>, <a href=\"mesencephalic_reticular_activating_system\">Mesencephalic reticular activating system<\/a>, <a href=\"motoneuron\">Motoneuron<\/a>, <a href=\"motor_cortex\">Motor cortex<\/a>, <a href=\"parkinson-s_disease\">Parkinson&#8217;s disease<\/a>, <a href=\"primary_motor_cortex\">Primary motor cortex<\/a>, <a href=\"red_nucleus\">Red nucleus<\/a>, <a href=\"spinal_cord\">Spinal cord<\/a>, <a href=\"thalamus\">Thalamus<\/a><\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The phylogenetically older one of two pyramidal systems that originate in the motor cortex, the other being the pyramidal system (or corticospinal tract). &nbsp;Together, they are responsible for the control and coordination of voluntary movements, as well as the maintenance of balance and posture. &nbsp;Thus, they are not functionally independent of each other, and interact &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/extrapyramidal_system\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Extrapyramidal system&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7929","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7929"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7929\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}