{"id":7962,"date":"2019-05-22T16:02:32","date_gmt":"2019-05-22T16:02:32","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/filopodia\/"},"modified":"2019-05-22T16:02:32","modified_gmt":"2019-05-22T16:02:32","slug":"filopodia","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/filopodia\/","title":{"rendered":"Filopodia"},"content":{"rendered":"<\/p>\n<\/p>\n<p>Filopodia (singular filopodium) are action-rich bulbous-shaped protrusions that function like antennae for a cell to probe the surrounding extracellular environment. &nbsp;They are 60-200 <a href=\"http:\/\/www.techterms.com\/definition\/nanometer\" target=\"_self\" data-editable-link=\"http:\/\/www.techterms.com\/definition\/nanometer&amp;target=_self\" rel=\"noopener noreferrer\">nm<\/a> in diameter made of parallel bundles of 10-20 actin filaments. &nbsp;Filopodia are classified as pseudopodia (temporary protrusions and retractions of the cytoplasm of eukaryote cells). &nbsp;As such, they have a simpler molecular structure than cilia and flagella, and unlike them have an amoeboid movement. &nbsp;The initiation and elongation of filopodia are dependent on the regulation of polymerizartion, and the convergence of cross-connections among these filaments. &nbsp;Typically, they are embedded within or protruding from the lamilliopodia situated at the front of migratory cells, thus serving a crucial role in cell locomotion and migration. &nbsp;They are also evident in neurite growth cones and cells such as fibroblasts. &nbsp;During development, but before the emergence of dendritic spines, cortical dendrites exhibit very long, thin processes often without a filapodium. &nbsp;As the cortex develops, the dendritic filapodia, distinct from other filapodia, disappear and spines emerge. &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<\/p>\n<p>See  Actin, <a href=\"cell_locomotion\">Cell locomotion<\/a>, <a href=\"cell_migration\">Cell migration<\/a>, <a href=\"cilia\">Cilia<\/a>, <a href=\"dendrite\">Dendrite<\/a>, <a href=\"extracellular_matrix\">Extracellular matrix<\/a>, <a href=\"fibroblasts\">Fibroblasts<\/a>, <a href=\"flagella\">Flagella<\/a>, <a href=\"growth_cone\">Growth cone<\/a>, <a href=\"lamillipodia\">Lamillipodia<\/a>, <a href=\"neurite\">Neurite<\/a>, <a href=\"polymerization\">Polymerization<\/a>, Quantitative and qualitative regressions<\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Filopodia (singular filopodium) are action-rich bulbous-shaped protrusions that function like antennae for a cell to probe the surrounding extracellular environment. &nbsp;They are 60-200 nm in diameter made of parallel bundles of 10-20 actin filaments. &nbsp;Filopodia are classified as pseudopodia (temporary protrusions and retractions of the cytoplasm of eukaryote cells). &nbsp;As such, they have a simpler &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/filopodia\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Filopodia&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-7962","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=7962"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/7962\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=7962"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=7962"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=7962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}