{"id":8058,"date":"2019-05-22T16:03:34","date_gmt":"2019-05-22T16:03:34","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/glial-derived_neurotrophic_factor_-gdntf\/"},"modified":"2019-05-22T16:03:34","modified_gmt":"2019-05-22T16:03:34","slug":"glial-derived_neurotrophic_factor_-gdntf","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/glial-derived_neurotrophic_factor_-gdntf\/","title":{"rendered":"Glial-derived neurotrophic factor (GDNtF)"},"content":{"rendered":"<p>A natural body chemical produced by the brain and referred to as a nerve cell growth factor, which has been shown in animal trials to stimulate the growth of many types of neurons. &nbsp;With regard to dopamine neurons, it appears to coax dying ones back into production, and thus has come to the forefront as a potential treatment for Parkinson&#8217;s disease. &nbsp;To date, however, the outcomes of human clinical trials using this growth factor have not been encouraging.&nbsp;<\/p>\n<p>See Axonal retraction (or pruning), <a href=\"nerve_growth_factor_-ngf-\">Nerve growth factor (NGF)<\/a>, <a href=\"neurotrophic_growth_factor_-ntgf-\">Neurotrophic growth factor (NtGF)<\/a>, <a href=\"parkinson-s_disease\">Parkinson&#8217;s disease<\/a><\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A natural body chemical produced by the brain and referred to as a nerve cell growth factor, which has been shown in animal trials to stimulate the growth of many types of neurons. &nbsp;With regard to dopamine neurons, it appears to coax dying ones back into production, and thus has come to the forefront as &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/glial-derived_neurotrophic_factor_-gdntf\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Glial-derived neurotrophic factor (GDNtF)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8058","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8058","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8058"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8058\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8058"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8058"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8058"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}