{"id":8352,"date":"2019-05-22T16:06:47","date_gmt":"2019-05-22T16:06:47","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/locus_coeruleus_-or_ceruleus\/"},"modified":"2019-05-22T16:06:47","modified_gmt":"2019-05-22T16:06:47","slug":"locus_coeruleus_-or_ceruleus","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/locus_coeruleus_-or_ceruleus\/","title":{"rendered":"Locus coeruleus (or ceruleus)"},"content":{"rendered":"<p>A small, bluish region on either side of the pons in the brain stem that lies near the lateral wall of the fourth ventricle. &nbsp;It consists of some 20,000 melanin-pigmented cell bodies (hence it is also referred to as the pigmentosus pontis), and contains the generally excitatory catecholamine neurotransmitter norepinephrine (or noradrenaline). &nbsp;Consequently, it is considered to an important brain center for anxiety and fear, as well as for the maintenance of arousal and vigilance more generally. &nbsp;Another of its functions appears to be its involvement in the initiation of REM sleep following a bout of slow-wave sleep. &nbsp;While the specific terminations of its neurons have not been clearly identified, their axons have a widespread distribution in the cerebral cortex, the cerebellum, the hypothalamus, and the spinal cord (see figure below).&nbsp;<\/p>\n<p style=\"text-align: center;\" class=\"\">\n<p><img decoding=\"async\" src=\"..\/wp-content\/uploads\/2019\/05\/image074.-locus-coeruleusjpg.jpg\" \/><\/div>\n<\/div>\n<p style=\"text-align: center;\" class=\"\">&nbsp;Locus coeruleus located in the brain stem from where the noradrenergic neurotransmitter system originates, and which has widespread projections to all levels of the nervous system.<\/p>\n<p style=\"text-align: left;\" class=\"\">See Arousal, Brain stem, Catecholamines, Cerebellum, Cerebral cortex (or pallium), EEG stage 3 sleep, Entorhinal cortex, Hypothalamus, Inhibitory control, Mesencephalic reticular activating system, Noradrenergic neurotransmitter system, Norephinephrine (or noradrenaline), Pituitary gland, Pons, Raphe nuclei, REM sleep, Spinal cord, Ventricle<\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A small, bluish region on either side of the pons in the brain stem that lies near the lateral wall of the fourth ventricle. &nbsp;It consists of some 20,000 melanin-pigmented cell bodies (hence it is also referred to as the pigmentosus pontis), and contains the generally excitatory catecholamine neurotransmitter norepinephrine (or noradrenaline). &nbsp;Consequently, it is &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/locus_coeruleus_-or_ceruleus\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Locus coeruleus (or ceruleus)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8352","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8352"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8352\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}