{"id":8370,"date":"2019-05-22T16:06:58","date_gmt":"2019-05-22T16:06:58","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/marfan_syndrome\/"},"modified":"2019-05-22T16:06:58","modified_gmt":"2019-05-22T16:06:58","slug":"marfan_syndrome","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/marfan_syndrome\/","title":{"rendered":"Marfan syndrome"},"content":{"rendered":"<p>A disorder inherited as an autosomal dominant trait and marked by defective formation of elastic fibers that affects the skeleton, large arteries, suspensory ligaments of the lens of the eye, tendons, and joint capsules. &nbsp;If afflicts 1\/5000 to 1\/10,000 people, making it more common, for example, than cystic fibrosis. &nbsp;Sufferers have abnormally long slender extremities, spidery fingers (see figure a below), high palate, displacement of the lens, lax joints (see figure b below), and aneurysm of the aorta. &nbsp;There is speculation that Abraham Lincoln suffered from Marfan syndrome. &nbsp;First described by the pediatrician <a href=\"http:\/\/www.whonamedit.com\/doctor.cfm\/972.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.whonamedit.com\/doctor.cfm\/972.html&amp;target=_self\" rel=\"noopener noreferrer\">Antoine Marfan<\/a> (1858-1942) in 1896.&nbsp;<\/p>\n<p style=\"text-align: center;\" class=\"\">\n<div id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb\" class=\"block wrapchrome image file\" data-guid=\"c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb\" data-type=\"image\" contenteditable=\"false\" data-file-guid=\"a4446c38-9868-416e-b380-1e8e3c51f469\" data-file-data-guid=\"3ad1f6db-2f16-43dd-8f7d-f7a47ca0d27d\">\n<div id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-wrapper\" class=\"wrapper wrapchrome\">\n<div id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-inner\" class=\"inner wrapchrome\">\n<div id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-inner-delete\" class=\"delete clickable chrome\">Delete this content<\/div>\n<div class=\"lock chrome\">\n<div class=\"lockedby\"><\/div>\n<\/div>\n<p><a id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-inner-debug\" class=\"debug chrome\" title=\"c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb\">[Debug]<\/a><\/p>\n<div class=\"content selectable wrapchrome\">\n<div class=\"container wrapchrome\">\n<div id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-container-delete\" class=\"delete clickable chrome\">Delete this content<\/div>\n<div class=\"placeholder chrome\">\n<h2>Loading\u2026<\/h2>\n<\/div>\n<div class=\"image wrapchrome\"><img decoding=\"async\" id=\"image-block-view-c57627fe-e2d4-e2d4-942e-d3ea3a3cdfbb-container-image-img\" class=\"clickable cc-routeable\" data-route-href=\"\" src=\".\/Lancaster Glossary of Child Development - Marfan syndrome_files\/3ad1f6db-2f16-43dd-8f7d-f7a47ca0d27d\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: center;\" class=\"\">Two physical characteristics of Marfan syndrome: spidery fingers (a) and lax joints (b).&nbsp;<\/p>\n<p>See <a href=\"autosomal_dominant_condition-disease\">Autosomal dominant condition\/disease<\/a>, <a href=\"hypotonia\">Hypotonia<\/a><\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A disorder inherited as an autosomal dominant trait and marked by defective formation of elastic fibers that affects the skeleton, large arteries, suspensory ligaments of the lens of the eye, tendons, and joint capsules. &nbsp;If afflicts 1\/5000 to 1\/10,000 people, making it more common, for example, than cystic fibrosis. &nbsp;Sufferers have abnormally long slender extremities, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/marfan_syndrome\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Marfan syndrome&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8370","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8370"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8370\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8370"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8370"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}