{"id":8437,"date":"2019-05-22T16:07:41","date_gmt":"2019-05-22T16:07:41","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/modern_synthesis\/"},"modified":"2019-05-22T16:07:41","modified_gmt":"2019-05-22T16:07:41","slug":"modern_synthesis","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/modern_synthesis\/","title":{"rendered":"Modern synthesis"},"content":{"rendered":"<p>The starting point was the rediscovery of Mendelian particulate genetics to account for Darwinian variation, the identification of the egrm plasm of <a href=\"http:\/\/www.princeton.edu\/~achaney\/tmve\/wiki100k\/docs\/August_Weismann.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.princeton.edu\/~achaney\/tmve\/wiki100k\/docs\/August_Weismann.html&amp;target=_self\" rel=\"noopener noreferrer\">August Weismann<\/a>&nbsp;(1834-1914) with Mendelian heredity factors and the evolvement of the chromosome theory of the gene by <a href=\"http:\/\/www.nndb.com\/people\/048\/000127664\/\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.nndb.com\/people\/048\/000127664\/&amp;target=_self\" rel=\"noopener noreferrer\">Thomas H. Morgan<\/a> (1866-1945). &nbsp;Building on Neo-Darwinism, the <a href=\"http:\/\/darwin200.christs.cam.ac.uk\/pages\/index.php?page_id=f5\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/darwin200.christs.cam.ac.uk\/pages\/index.php?page_id=f5?target=_self\" rel=\"noopener noreferrer\">synthesis itself began in the 1920s<\/a>. &nbsp;It involved the replacement of Mendelian genetics by the mathematical formulations of population genetics that deals with gene ratios in groups of organisms, their integration with Darwin&#8217;s original theory of natural selection and an emphasis on phyletic gradualism. &nbsp;Key figures in this respect were <a href=\"http:\/\/russia-ic.com\/people\/general\/c\/151\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/russia-ic.com\/people\/general\/c\/151&amp;target=_self\" rel=\"noopener noreferrer\">Sergei S. Chetverikov<\/a> (1880-1959), <a href=\"http:\/\/mnstats.morris.umn.edu\/introstat\/history\/w98\/RAFisher.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/mnstats.morris.umn.edu\/introstat\/history\/w98\/RAFisher.html&amp;target=_self\" rel=\"noopener noreferrer\">Ronald A. Fisher<\/a> (1890-1962), <a href=\"http:\/\/www.0095.info\/en\/index_thesesen_95onesentencethesesagainste_thehumanandchimpanzeegenomes.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.0095.info\/en\/index_thesesen_95onesentencethesesagainste_thehumanandchimpanzeegenomes.html&amp;target=_self\" rel=\"noopener noreferrer\">John B.S. Haldane <\/a>(1892-1964), <a href=\"http:\/\/www.harvardsquarelibrary.org\/unitarians\/wright-sewall.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.harvardsquarelibrary.org\/unitarians\/wright-sewall.html&amp;target=_self\" rel=\"noopener noreferrer\">Sewall Wright<\/a> (1889-1988) and <a href=\"http:\/\/www.pbs.org\/wgbh\/evolution\/library\/06\/2\/l_062_04.html\" class=\"cc-route-enabled\" target=\"_self\" data-editable-link=\"http:\/\/www.pbs.org\/wgbh\/evolution\/library\/06\/2\/l_062_04.html&amp;target=_self\" rel=\"noopener noreferrer\">Theodosius Dobzhansky <\/a>(1900-1975), whose book <span class=\"\" style=\"font-style: italic;\">Genetics and the origin of species<\/span> published in 1937 can be taken as the first comprehensive outline of the synthesis. &nbsp;It differed from Neo-Darwinism in no longer holding to a one-to-one correspondence between genes and heritable characters, but rather many-to-one and one-to-many correspondences. &nbsp;Furthermore, it defined natural selection in terms of differential reproductive success without reference to phenotypic fitness ensuring individual fitness. &nbsp;In other respects, it left Neo-Darwinism unchanged. &nbsp;Like Neo-Darwinism, it treated ontogenetic development as being largely irrelevant for understanding biological evolution. &nbsp;This neglect of ontogenetic development led to criticisms of the Modern synthesis over the years and to the present attempt by evolutionary developmental biology to forge a new synthesis that includes it.&nbsp;<\/p>\n<p>See <a href=\"adaptation\">Adaptation<\/a>, <a href=\"biological_evolution\">Biological evolution<\/a>, <a href=\"central_dogma_of_molecular_biology\">Central dogma of molecular biology<\/a>, <a href=\"darwinism\">Darwinism<\/a>, <a href=\"developmental_biology\">Developmental biology<\/a>, <a href=\"evolutionary_developmental_biology\">Evolutionary developmental biology<\/a>, <a href=\"fisher-s_theory_of_evolutionary_mimicry\">Fisher&#8217;s theory of evolutionary mimicry<\/a>, Founder effect, <a href=\"genetic_assimilation\">Genetic assimilation<\/a>, <a href=\"germ_plasm\">Germ plasm<\/a>, &#8216;Hopeful&#8217; monsters, <a href=\"lamarckism\">Lamarckism<\/a>, <a href=\"macroevolution_-or_horizontal_evolution-_and_micro\">Macroevolution (or horizontal evolution) and microevolution (or vertical evolution)<\/a>, <a href=\"mendelian_genetics\">Mendelian genetics<\/a>, <a href=\"natural_selection\">Natural selection<\/a>, <a href=\"neo-darwinism\">Neo-Darwinism<\/a>, <a href=\"phyletic_gradualism_and_punctuated_equilibrium\">Phyletic gradualism and punctuated equilibrium<\/a>, <a href=\"population_genetics\">Population genetics<\/a>, <a href=\"recapitulation_theory_-or_biogenetic_law-\">Recapitulation theory (or biogenetic law)<\/a>, <a href=\"tautology\">Tautology<\/a>, Theory of natural selection <\/p>\n<p><\/p>\n<p><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The starting point was the rediscovery of Mendelian particulate genetics to account for Darwinian variation, the identification of the egrm plasm of August Weismann&nbsp;(1834-1914) with Mendelian heredity factors and the evolvement of the chromosome theory of the gene by Thomas H. Morgan (1866-1945). &nbsp;Building on Neo-Darwinism, the synthesis itself began in the 1920s. &nbsp;It involved &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/modern_synthesis\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Modern synthesis&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8437","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8437","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8437"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8437\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8437"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8437"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8437"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}