{"id":8731,"date":"2019-05-22T16:10:54","date_gmt":"2019-05-22T16:10:54","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/phenylketonuria_-pku\/"},"modified":"2019-05-22T16:10:54","modified_gmt":"2019-05-22T16:10:54","slug":"phenylketonuria_-pku","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/phenylketonuria_-pku\/","title":{"rendered":"Phenylketonuria (PKU)"},"content":{"rendered":"<p>A recessive genetic disorder that leads to functional&nbsp;deficits in children arising from a neurochemical deficit in the prefrontal cortex (i.e., the enzyme converting dietary phenylalanine to tyrosine is deficient, resulting in the excretion of phenylpyruvate, or phenylalanine, into the urine). &nbsp;While cognitive impairment is common and about 25% of cases have epileptic attacks, it can be detected soon after birth and treated with a low diet of phenylalanine.<\/p>\n<p>See <a href=\"guthrie_test\">Guthrie test<\/a>, <a href=\"epilepsy\">Epilepsy<\/a><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recessive genetic disorder that leads to functional&nbsp;deficits in children arising from a neurochemical deficit in the prefrontal cortex (i.e., the enzyme converting dietary phenylalanine to tyrosine is deficient, resulting in the excretion of phenylpyruvate, or phenylalanine, into the urine). &nbsp;While cognitive impairment is common and about 25% of cases have epileptic attacks, it can &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/phenylketonuria_-pku\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Phenylketonuria (PKU)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8731","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8731"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8731\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}