{"id":8843,"date":"2019-05-22T16:12:07","date_gmt":"2019-05-22T16:12:07","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/progress_zone\/"},"modified":"2019-05-22T16:12:07","modified_gmt":"2019-05-22T16:12:07","slug":"progress_zone","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/progress_zone\/","title":{"rendered":"Progress zone"},"content":{"rendered":"<p>The zone consists of mesodermal cells and is situated underneath the apical ectodermal ridge of the vertebrate limb bud (see figure below).&nbsp;&nbsp;It acts to provide positional information that enables cells to develop into a limb.&nbsp;The transmission of this information appears to depend on the time the cells spend in the zone during outgrowth of the bud (proximal-distal axis of the limb): the shorter the time, the more it receives signals from the ridge (with timing perhaps determined by&nbsp;<a href=\"https:\/\/biologydictionary.net\/transcription-factor\/\" target=\"_self\" data-editable-link=\"https:\/\/biologydictionary.net\/transcription-factor\/?target=_self\" rel=\"noopener noreferrer\">transcription factors<\/a>).&nbsp;&nbsp;Alternatively, some research suggests the cells are prespecified.&nbsp;&nbsp;&nbsp;<\/p>\n<p><img decoding=\"async\" src=\"..\/wp-content\/uploads\/2019\/05\/Presentation1.jpg\" \/><\/div>\n<\/div>\n<p style=\"text-align: right;\" class=\"\"><\/p>\n<p style=\"text-align: center;\" class=\"\">Progress zone in the posterior(edge of)&nbsp;&nbsp;mesoderm of the developing vertebrate limb bud indicating the position of the apical ectodermal ridge.&nbsp;&nbsp;The polarizing activity in the zone acts as a crucial signalling center and together with other interconnected centers ensures a coordinated function in limb growth patterning.&nbsp;&nbsp;<\/p>\n<p>See <a href=\"apical_ectodermal_ridge_-aer-\">Apical ectodermal ridge (AER)<\/a>, <a href=\"limb_bud\">Limb bud<\/a>, <a href=\"mesoderm\">Mesoderm<\/a><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The zone consists of mesodermal cells and is situated underneath the apical ectodermal ridge of the vertebrate limb bud (see figure below).&nbsp;&nbsp;It acts to provide positional information that enables cells to develop into a limb.&nbsp;The transmission of this information appears to depend on the time the cells spend in the zone during outgrowth of the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/progress_zone\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Progress zone&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-8843","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=8843"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/8843\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=8843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=8843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=8843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}