{"id":9011,"date":"2019-05-22T16:13:56","date_gmt":"2019-05-22T16:13:56","guid":{"rendered":"http:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/selectins\/"},"modified":"2019-05-22T16:13:56","modified_gmt":"2019-05-22T16:13:56","slug":"selectins","status":"publish","type":"post","link":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/selectins\/","title":{"rendered":"Selectins"},"content":{"rendered":"<p>A small family of integral membrane proteins &nbsp;(viz., cell adhesion molecules) that bind to particular oligosaccharides projecting from the surface of other cells. &nbsp;They are important for white blood cell (leucocyte) binding to blood vessel walls and for migration to sites of infection or inflammation. &nbsp;Three such molecules have been identified:&nbsp;P-selectin (CD62P), E-selectin (CD62E) and L-selectin (CD62L), involved in slowing leucocytes during their transit through venues.<\/p>\n<p>&nbsp;See <a href=\"cadherins\">Cadherins<\/a>, <a href=\"cell_adhesion_molecules_-cams-\">Cell adhesion molecules (CAMs)<\/a>, <a href=\"mucins\">Mucins<\/a>, <a href=\"oligosaccharides\">Oligosaccharides<\/a>, <a href=\"integrins\">Integrins<\/a>, <a href=\"venule\">Venule<\/a><\/p>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A small family of integral membrane proteins &nbsp;(viz., cell adhesion molecules) that bind to particular oligosaccharides projecting from the surface of other cells. &nbsp;They are important for white blood cell (leucocyte) binding to blood vessel walls and for migration to sites of infection or inflammation. &nbsp;Three such molecules have been identified:&nbsp;P-selectin (CD62P), E-selectin (CD62E) and &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/selectins\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Selectins&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2],"class_list":["post-9011","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-glossary","entry"],"_links":{"self":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/9011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/comments?post=9011"}],"version-history":[{"count":0,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/posts\/9011\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/media?parent=9011"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/categories?post=9011"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lancaster.ac.uk\/fas\/psych\/glossary\/wp-json\/wp\/v2\/tags?post=9011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}