Cancer Biology and DNA Damage

Members of this research group contribute to the cross-faculty research theme on Ageing.

This research group is carrying out work directed towards understanding the cellular and molecular basis of cancer.

Projects looking specifically at the underlying causes of malignancies such as colorectal, prostate and skin cancer are currently ongoing, while characterisation of the cellular response to DNA damage and the related topic of cell division control are also key themes within our work.


Researchers working in this area, together with a short description of their research interests, are listed below.

  • Dr Sarah Allinson: Eukaryotic DNA Repair; Effects of UV Radiation on Human Skin Cells; Heavy Metal Carcinogenesis
  • Dr Alexandre Benedetto: Cell cycle regulation, lab on a chip approaches to studying cancer progression
  • Dr Fiona Benson: DNA repair, homologous recombination
  • Dr Nikki Copeland: Regulation of DNA Replication, cancer cell proliferation
  • Dr Howard Lindsay: (Lancaster Medical School) Cell Signalling Pathways Related to DNA Replication and DNA Damage
  • Dr Richard Mort: Melanocyte development, melanoma, and tissue homeostasis
  • Dr Edward Parkin: ADAM Proteases; Prostate Cancer
  • Dr Rachael Rigby: Colorectal Cancer; Intestinal Epithelial Cell Homeostasis
  • Dr Nick Robinson: Archael models; DNA replication, DNA repair, protein homeostasis and genomic stability
  • Dr Elaine Taylor: (Lancaster Medical School) Eukaryotic DNA Repair; DNA Replication; Cell Division; Post-translational Modification
  • Dr Leonie Unterholzner: The innate immune response to DNA damage, skin cancer
  • Dr Karen Wright: Colorectal Cancer; Cannabinoids