Professor Roger Pickup


Research Overview

My research interests lie in 'Environment and human health' with expertise in molecular microbial ecology/environmental microbiology. I am particularly interested in non-tuberculous mycobacteria and their environmental routes for human exposure. Of main interest is Mycobacterium avium subspecies paratuberculosis (Map) which causes inflammatory bowel disease (Johne’s disease) in the majority of animals. With collaborators, we are examining Map’s role in Crohn’s disease, a similar human inflammatory condition. Map is significantly associated with this crippling disease and we seek to ascertain whether it is the cause. Other interests include: antibiotic resistance in the natural and hospital environments, gene transfer in the environment and diversity of bacteria in bird guts and in those involved in bee nutrition.

Influenza C in Lancaster, UK, in the winter of 2014-2015
Atkinson, K.V., Bishop, L.A., Rhodes, G., Salez, N., McEwan, N.R., Hegarty, M.J., Robey, J., Harding, N., Wetherell, S., Lauder, R.M., Pickup, R.W., Wilkinson, M., Gatherer, D. 13/04/2017 In: Scientific Reports. 7, 9 p.
Journal article

Genome sequence of human rhinovirus A22, strain Lancaster/2015
Atkinson, K.V., Bishop, L.A., Rhodes, G., Salez, N., McEwan, N.R., Hegarty, M.J., Robey, J., Harding, N., Wetherell, S., Lauder, R.M., Pickup, R.W., Wilkinson, M., Gatherer, D. 23/03/2017 In: Genome Announcements. 5, 12
Journal article

Contract Researcher Audit and Survey–Foundation Report
Brown, J.C., Shaw, E.J., Pickup, R.W., Morbey, H. 01/2017 Lancaster : Lancaster University.
Other report

Carbapenemase-producing Enterobacteriaceae in hospital wastewater: a reservoir that may be unrelated to clinical isolates [star]
White, L., Hopkins, K., Meunier, D., Perry, C.L., Pike, R., Wilkinson, P., Pickup, R.W., Cheesbrough, J., Woodford, N. 06/2016 In: Journal of Hospital Infection. 93, 2, p. 145-151. 7 p.
Journal article

Immobilization of Shewanella oneidensis MR-1 in diffusive gradients in thin films for determining metal bioavailability
Baker, P., Hogstrand, C., Lead, J., Pickup, R., Zhang, H. 11/2015 In: Chemosphere. 138, p. 309-315. 7 p.
Journal article

Life history correlates of faecal bacterial species richness in a wild population of the blue tit Cyanistes caeruleus
Benskin, C., Rhodes, G., Pickup, R., Mainwaring, M., Wilson, K., Hartley, I. 02/2015 In: Ecology and Evolution. 5, 4, p. 821-835. 15 p.
Journal article

Honeybee nutrition is linked to landscape composition
Donkersley, P., Rhodes, G., Pickup, R., Jones, K., Wilson, K. 11/2014 In: Ecology and Evolution. 4, 21, p. 4195-4206 . 12 p.
Journal article

The rulB gene of plasmid pWW0 is a hotspot for the site-specific insertion of integron-like elements found in the chromosomes of environmental Pseudomonas fluorescens group bacteria
Rhodes, G., Bosma, H., Studholme, D., Arnold, D., Robert, J., Pickup, R. 1/09/2014 In: Environmental Microbiology. 16, 8, p. 2374-2388 . 15 p.
Journal article

Mycobacterium avium subspecies paratuberculosis: human exposure through environmental and domestic aerosols
Rhodes, G., Richardson, H., Hermon-Taylor, J., Weightman, A., Higham, A., Pickup, R. 14/07/2014 In: Pathogens. 3, 3, p. 577-595. 19 p.
Journal article

Wrong, but useful: negotiating uncertainty in infectious disease modelling
Christley, R., Mort, M., Wynne, B., Wastling, J., Heathwaite, L., Pickup, R., Austin, Z., Latham, S. 16/10/2013 In: PLoS ONE. 8, 10, 13 p.
Journal article

Mycobacterium avium subspecies paratuberculosis is widely distributed in British soils and waters: implications for animal and human health
Rhodes, G., Hentys, P., Thomson, B., Pickup, R. 10/2013 In: Environmental Microbiology. 15, 10, p. 2761-2774. 14 p.
Journal article

Diversity of planktonic and attached bacterial communities in a phenol-contaminated sandstone aquifer.
Rizoulis, A., Elliot, D.R., Rolfe, S.A., Thornton, S.F., Banwart, S.A., Pickup, R.W., Scholes, J.D. 1/07/2013 In: Microbial Ecology. 66, 1, p. 84-95. 12 p.
Journal article

Policy, practice and decision making for zoonotic disease management: water and cryptosporidium
Austin, Z., Alcock, R., Christley, R., Haygarth, P., Heathwaite, L., Latham, S., Mort, M., Oliver, D., Pickup, R., Wastling, J.M., Wynne, B. 04/2012 In: Environment International. 40, n/a, p. 70-78. 9 p.
Journal article

The bacteriology of Windermere and its catchments: insights from 70 years of study
Rhodes, G., Porter, J., Pickup, R. 02/2012 In: Freshwater Biology. 57, 2, p. 305-320. 16 p.
Journal article

Uncertainties in the governance of animal disease: an interdisciplinary framework for analysis
Fish, R., Austin, Z., Christley, R., Haygarth, P.M., Heathwaite, A.L., Heathwaite, L.A., Latham, S., Medd, W., Mort, M., Oliver, D.M., Pickup, R., Wastling, J.M., Wynne, B. 27/09/2011 In: Philosophical Transactions B: Biological Sciences. 366, 1573, p. 2023-2034. 12 p.
Journal article

Implementation of a quantitative real-time PCR assay for the detection of mycobacterium immunogenum in metalworking fluids
Rhodes, G., Fluri, A., Ruefenacht, A., Gerber, M., Pickup, R. 08/2011 In: Journal of Occupational and Environmental Hygiene. 8, 8, p. 478-483. 6 p.
Journal article

Assessment of MTBE biodegradation in contaminated groundwater using 13C and 14C analysis: field and laboratory microcosm studies
Thornton, S., Bottrell, S., Spence, K., Pickup, R., Spence, M., Mallinson, H., Shah, N., Richnow, H. 05/2011 In: Applied Geochemistry. 26, 5, p. 828-837. 9 p.
Journal article

Diversity and temporal stability of bacterial communities in a model passerine bird, the zebra finch.
Benskin, C., Rhodes, G., Pickup, R.W., Wilson, K., Hartley, I.R. 12/2010 In: Molecular Ecology. 19, 24, p. 5531-5544. 14 p.
Journal article

Engaging with the water sector for public health benefits: waterborne pathogens and diseases in developed countries
Bridge, J.W., Oliver, D.M., Chadwick, D., Godfray, H.C.J., Heathwaite, A.L., Kay, D., Maheswaran, R., McGonigle, D.F., Nichols, G., Pickup, R., Porter, J., Wastling, J., Banwart, S.A. 11/2010 In: Bulletin of the World Health Organization. 88, 11, 3 p.

The effect of bacterial prey species and their concentration on growth of the amoebae Acanthamoeba castellanii and Hartmannella vermiformis.
Pickup, Z.L., Pickup, R., Parry, J.D. 04/2007 In: Applied and Environmental Microbiology. 73, 8, p. 2631-2634. 4 p.
Journal article

A comparison of the growth and starvation responses of Acanthamoeba castellanii and Hartmannella vermiformis in the presence of suspended and attached Escherichia coli K12
Pickup, Z.L., Pickup, R., Parry, J.D. 2007 In: FEMS Microbiology Ecology. 59, 3, p. 556-563. 8 p.
Journal article

Growth of Acanthamoeba castellanii and Hartmannella vermiformis on live, heat-killed and DTAF-stained bacterial prey
Pickup, Z.L., Pickup, R., Parry, J.D. 2007 In: FEMS Microbiology Ecology. 61, 2, p. 264-272. 9 p.
Journal article

Mechanisms for soil resistance.
Pickup, R., Rhodes, G. 28/04/2006 In: Science. 312, 5773, 1 p.

Review of the Predatory Bird Monitoring Scheme (PBMS).
Shore, R.F., Walker, L., Thomas, G.O., Barber, J.L., Martin, F.R., Jones, K.C., Beresford, N.A., Rowland, P., Pickup, R.W. 2006 Unknown Publisher.

The potential harbouring of coliform bacteria by protozoa in biofilms.
English, J., Pickup, R., Parry, J.D. 2001 In: Biofilm community interactions : chance or necessity?. Cardiff : Bioline p. 271-279. 9 p.