Dr Christine Shirras

Senior Teaching Fellow


Academic Qualifications

1993 B.Sc. Chemistry, Lancaster University 1997 Ph.D. Molecular Biology, Lancaster University 2001 Certificate in Learning and Teaching in Higher Education 2005 Postgraduate Certificate of Education (PGCE)

Career History

1997-2000 Post Doctoral Research Associate, Lancaster University 2000 Lecturer in Eukaryotic Molecular Biology, University of Central Lancashire 2000-2001 Clinical Biochemist, Royal Lancaster Infirmary 2002-2004 Post Doctoral Research Associate, Lancaster University 2004-2007 Part-time lecturer, Lancaster University 2006 Part-time Post Doctoral Research Associate Lancaster University 2007 - Present. Teaching Fellow Lancaster University

lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
Nagy, O., Pal, M., Udvardy, A., Shirras, C.A.M., Boros, I., Shirras, A.D., Deak, P. 14/03/2012 In: Cell Division. 7, n/a, 16 p.
Journal article

Peptidomics and Peptide Hormone Processing in the Drosophila Midgut
Reiher, W., Shirras, C., Kahnt, J., Baumeister, S., Isaac, R.E., Wegener, C. 04/2011 In: Journal of Proteome Research. 10, 4, p. 1881-1892. 12 p.
Journal article

Loss of Angiotensin-converting enzyme-related (ACER) peptidase disrupts night-time sleep in adult Drosophila melanogaster
Carhan, A., Tang, K., Shirras, C.A., Shirras, A.D., Isaac, R.E. 02/2011 In: Journal of Experimental Biology. 214, 4, p. 680-686. 7 p.
Journal article

Increased fragmentation of night-time sleep in Drosophila melanogaster lacking the angiotensin-converting enzyme-related (ACER) peptidase
Isaac, E., Carhan, A., Tang, K., Shirras, C., Shirras, A. 2009
Meeting abstract

Angiotensin-converting enzyme as a target for the development of novel insect growth regulators.
Isaac, R.E., Lamango, N.S., Ekbote, U., Taylor, C.A., Hurst, D., Weaver, R.J., Carhan, A., Burnham, S., Shirras, A.D. 01/2007 In: Peptides. 28, 1, p. 153-162. 10 p.
Journal article

Expression and function of proctolin in Drosophila
Shirras, A.D., Taylor, C.A.M., Nassel, D.R., Coast, G.M., Isaac, R.E. 07/2005
Meeting abstract

Proctolin in the post-genomic era: new insights and challenges
Isaac, R.E., Taylor, C.A., Hamasaka, Y., Nässel, D.R., Shirras, A.D. 10/2004 In: Invertebrate Neuroscience. 5, 2, p. 51-64. 14 p.
Journal article

Detection of specific antibodies in cord blood, infant and maternal saliva and breast milk to staphylococcal toxins implicated in sudden infant death syndrome (SIDS)
Harrison, L.M., Morris, J.A., Bishop, L.A., Lauder, R.M., Taylor, C.A.M., Telford, D.R. 1/09/2004 In: FEMS Immunology and Medical Microbiology. 42, 1, p. 94-104. 11 p.
Journal article

Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: Expression and predicted prohormone processing
Taylor, C.A.M., Winther, A.M.E., Siviter, R.J., Shirras, A.D., Isaac, R.E., Nassel, D.R. 15/02/2004 In: Journal of Neurobiology. 58, 3, p. 379-391. 13 p.
Journal article

Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone.
Siviter, R.J., Taylor, C.A.M., Cottam, D.M., Denton, A., Dani, M.P., Milner, M.J., Shirras, A.D., Isaac, R.E. 1/10/2002 In: Biochemical Journal. 367, 1, p. 187-193. 7 p.
Journal article

Expression and functional characterisation of a Drosophila neuropeptide precursor with homology to mammalian preprotachykinin.
Siviter, R.J., Coast, G.M., Winther, Å.M., Nachman, R.J., Taylor, C.A.M., Shirras, A.D., Coates, D., Isaac, R.E., Nässel, D.R. 28/07/2000 In: Journal of Biological Chemistry. 275, 30, p. 23273-23280. 8 p.
Journal article

The Orct gene of Drosophila melanogaster codes for a putative organic cation transporter with six or 12 transmembrane domains
Taylor, C.A.M., Stanley, K.N., Shirras, A.D. 12/11/1997 In: Gene. 201, 1-2, p. 69-74. 6 p.
Journal article

The Acer gene of Drosophila codes for an angiotensin-converting enzyme homologue.
Taylor, C.A.M., Coates, D., Shirras, A.D. 11/1996 In: Gene. 181, 1-2, p. 191-197. 7 p.
Journal article