Funded research

Funded research projects

MARS academics and researchers secure competitive grant funding to tackle complex challenges at the interface of applied mathematics and machine learning. Working with partners in academia, industry and government, our funded projects span environmental science, health, engineering and fundamental AI research.

A pipette dropping clear liquid into a test tube surrounded by other test tubes.

Accelerating Scientific Discovery in the Age of Generative AI

  • Funder: UKRI (Future Leaders Fellowship)
  • Project Lead: Dr Henry Moss, MARS

Recent AI advances, typified by large language models like ChatGPT, have been driven by systems that can generate and analyse vast volumes of data in milliseconds. The next frontier of AI development lies in domains where data are inherently scarce, noisy, and costly to obtain, such as laboratory science and industrial R&D.

In these domains, progress has long relied on sequential experimental design, which uses rigorous mathematical principles to craft batches of experiments that extract the maximum possible insight from each measurement. However, classical mathematical principles of experimental design can no longer keep pace with modern science.

This fellowship will tackle this challenge by turning generative AI models into mathematically rigorous decision rules for designing real-world experimental campaigns. It will lead to scientific innovation in areas such as drug discovery and sustainable engineering.

Through the release of open-source software and by training a new generation of AI researchers, the fellowship will also strengthen the UK’s AI capability and competitiveness.

The research is supported by a network of universities across Europe and North America, and a range of industry partners.

More information about the fellowship is available here.

A brightly coloured fish swimming in front of a coral reef.

AI-Enabled Behavioural Ecology for Conservation (BEACON)

Conservation monitoring has traditionally relied on changes in species numbers or habitat condition. By the time such changes become apparent, ecosystems may already have suffered significant damage.

Animal behaviour often changes much earlier in response to environmental stress, and has the potential to serve as an early warning system. However, behavioural observation is time-consuming and, for this reason, has rarely been used in conservation practice. BEACON addresses this challenge using artificial intelligence.

BEACON will develop AI tools capable of recognising and tracking fish behaviour across extensive archives of underwater video, beginning with tropical coral reefs and extending to UK coastal waters. Field studies and experiments will establish how environmental disturbances alter animal behaviour, and how these changes affect the health of the wider ecosystem. The outcome will be practical tools to support conservation managers in identifying emerging problems and determining appropriate action.

BEACON brings together researchers in ecology and artificial intelligence with conservation organisations and international partners. These include institutions in Brazil and Portugal, the Seychelles Parks and Gardens Authority, Cefas, Natural England and Renew Earth.

A tropical rain forest.

Determination of Tropical Oxidising Capacity through Model Calibration (DeTOX)

The atmosphere possesses a natural oxidising capacity. Chemical reactions, driven largely by sunlight over the tropics, break down air pollutants and greenhouse gases. The effectiveness of this process determines how long these gases persist in the atmosphere, with significant implications for both air quality and climate change.

Policy decisions rely on atmospheric models, yet current models are inconsistent in how they simulate oxidising capacity. DeTOX will transform understanding of atmospheric oxidation in the tropics. By uncovering how physical, chemical and meteorological processes interact to control oxidation, DeTOX will provide the first robust attribution of the mechanisms shaping atmospheric composition.

This new knowledge will enable more accurate projections of how tropical development and climate change will alter the atmosphere, and has the potential to directly inform strategies to mitigate pollution and curb greenhouse gas emissions.

DeTOX is a collaboration between atmospheric scientists and machine learning specialists. The consortium includes partners at the universities of Bristol, Cambridge, Edinburgh, Exeter and Reading, and NASA and the NSF National Center for Atmospheric Research in the US.

A woman sitting on a bed looking out of a window.

Connecting Brain Networks and Hormones Together via Pseudospectra to Understand the Mechanisms of Depression

Depression is a leading cause of ill-health and disability worldwide. Different forms of depression are associated with distinct patterns of brain activity and stress hormone levels. Understanding these differences may help to explain why treatments are effective for some patients but not others.

This fellowship will use mathematical modelling to investigate how the body's stress hormone system interacts with brain regions involved in emotion and memory. It will develop computer models of these interconnected systems and analyse them using a mathematical technique known as pseudospectra. This approach reveals how disturbances, such as a stressful event, can produce significant temporary changes within a system.

By simulating stress responses and the effects of treatment, the fellowship aims to provide new insight into the mechanisms underlying depression and the variation in patients' responses to interventions. In the longer term, this could lead to personalised mental health care and more effective treatment for those with depression.

The fellowship involves interdisciplinary collaborations with academics from digital healthcare innovation, imaging neuroscience, computational neuroscience and medicine.

An ice sheet in the arctic.

IceDice: Predicting the Stochastic Behaviour of West Antarctica's Marine Ice Sheet

The West Antarctic Ice Sheet contains enough ice to raise global sea levels by up to five metres. The rate at which it will melt remains one of the greatest uncertainties in climate science, presenting significant challenges for coastal planning and policy.

IceDice aims to improve the reliability of ice melt predictions. Rather than producing a single forecast, the project will estimate the full range of possible outcomes and the likelihood of each, including rare but severe scenarios of rapid sea level rise.

To achieve this, the research team will develop more realistic models that represent both the fracturing of the ice and its interaction with a warming ocean. As running these models many thousands of times is impractical, the project will employ machine learning and statistical methods to create efficient approximations. These will allow a wider range of scenarios to be explored, with particular attention to the outcomes of greatest consequence.

IceDice is a collaboration between the British Antarctic Survey, King’s College London, Lancaster University and the London School of Economics. Its forecasts will provide decision-makers worldwide with a robust basis for planning cost-effective coastal adaptation.

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