Dr Lorna Ashton


Research Overview

My research group focuses on the advancement of Raman spectroscopy as a bioprocessing analytical technique and for single cell Raman mapping. I have extensive experience of combining Raman techniques including UV resonance Raman and Raman optical activity with chemometric methods for the identification of structural changes due to post-translational modifications, protein-protein interactions, ligand binding and changes in protein stability. I am presently extending this research into the area of Gene and Cell Therapies. Furthermore, we are developing Raman micro-spectroscopy techniques to image live cells grown on 3D micro-engineered scaffolds.

  • Analytical Chemistry and Spectroscopy