Dr Howard Lindsay

Lecturer in Biomedical Sciences & Year 1 Director

Research Overview

My main research interests are the mechanisms that maintain genome stability, in particular the cellular responses to DNA damage and DNA replication stress. Using Xenopus cell-free egg extracts as a model system, the primary aim of this work is a greater understanding of the way the various DNA damage response pathways are integrated with the cell cycle machinery and how failure of these pathways can contribute to the development and progression of cancer.