Ageing and Neuroscience research
Our research focuses on:
- normal ageing in model organisms
- the molecular mechanisms leading to brain dysfunction and degeneration in various neuronal and psychiatric disorders.
Our research into the underlying processes of healthy ageing involves study of the processes leading to brain dysfunction and degeneration.
Progressive degeneration of the nervous system, and hence impaired cognition or movement, is a characteristic of conditions as Alzheimer’s disease, Parkinson’s disease and motor neurone disease.
We seek improved biomarkers for these diseases, and to develop new treatments by repurposing existing drugs or developing new ones, with the aim of taking these drugs into clinical trials.
In researching psychiatric disorders such as schizophrenia, we focus on the mechanisms through which genetic and environmental risk factors effect brain functioning and behaviour, and on identification of novel drugs to treat these disorders.
Members of the group also work on other age-related diseases, such as eye disease, osteoarthritis and cardiovascular disease.