Two researchers examining scientific apparatus. Researchers are focused on their work

Cancer Biology and Genome Stability

Members of this research group contribute to the cross-faculty research theme on Ageing.

Cancer Research

Our research is aimed at understanding the cellular and molecular basis of cancer to develop better ways of preventing, diagnosing and treating the disease.

Genome stability is one major focus of our work - several of our research groups are studying how cells maintain the integrity of their DNA and how these processes can become disrupted in cancer.

We also have several groups who are interested in how other important cellular processes become disrupted in cancer and whether these can be targeted to develop new treatments or used as biomarkers to improve diagnosis.

We work closely with local charity North West Cancer Research, who fund both staff and individual projects in the Division.


Dr Sarah Allinson: Eukaryotic DNA Repair; Effects of UV Radiation on Human Skin Cells; Heavy Metal Carcinogenesis

Dr Alexandre Benedetto: Cell cycle regulation, lab on a chip approaches to studying cancer progression

Dr Fiona Benson: DNA repair, homologous recombination

Dr Nikki Copeland: Regulation of DNA Replication, cancer cell proliferation

Dr Howard Lindsay: (Lancaster Medical School) Cell Signalling Pathways Related to DNA Replication and DNA Damage

Dr Richard Mort: Melanocyte development, melanoma, and tissue homeostasis

Dr Andrew Fielding: Phenotype analysis

Dr Morgan Gadd: Oncoprotein degraders, PROTAC design

Dr Lucy Jackson-Jones: Thoaracic immune responses

Professor Paul O'Shea: Lipid analysis

Dr Edward Parkin: ADAM Proteases; Prostate Cancer
Dr Rachael Rigby: Colorectal Cancer; Intestinal Epithelial Cell Homeostasis
Dr Nick Robinson: Archael models; DNA replication, DNA repair, protein homeostasis and genomic stability
Dr Elaine Taylor: (Lancaster Medical School) Eukaryotic DNA Repair; DNA Replication; Cell Division; Post-translational Modification
Dr Leonie Unterholzner: The innate immune response to DNA damage, skin cancer
Dr Karen Wright: Colorectal Cancer; Cannabinoids
Dr Jemma Kerns: (Lancaster Medical School) Raman/IR spectroscopy, bone biology

Associate members
Dr John Worthington: Immunology, parasitology and endocrinology
Dr Muhammad Munir: Virology

Dr Mick Urbaniak: Molecular biology