of our Research Environment is rated world-leading
of our Research was judged to be world-leading or internationally excellent
Immunology, Parasitology and Microbiology research
Members of this research group contribute to the cross-faculty research theme on Infectious Disease Transmission and Biology.
Research in the Microbes, Pathogens and Immunity theme investigates the evolution, transmission and pathogenesis of microbes and their insect vectors as well as examining the function of the immune system in both health and disease. By examining the diverse and unusual biological mechanisms of microbes at the molecular level we seek to identify processes that can be targeted therapeutically or exploited for commercially.
Areas of focus
Some examples of our particular areas of interest and expertise are:
- Environmental exposure to harmful micro-organisms and impact on animal and human populations
- Evolution and spread of viruses
- Host immune response towards pathogenic and commensal microbes
- How Fat Associated Lymphoid Clusters orchestrate local immune responses within the body cavities
- How microbes sense and respond to their host environment to ensure their survival, transmission and virulence
- How gut microbes effect disease progression, recovery, and ageing
- Mapping insect vector population dynamics, dispersion, and distribution along environmental gradients
- Neglected tropical diseases and their insect vectors
- Optimisation of disease and vector surveillance and control
We enjoy access to advanced research facilities including:
- Biohazard Category III laboratory unit
- Biohazard Category II laboratory spaces and insectaries
- Advanced microscopy & bioimaging suite
- Analytical facilities including spectrophotometers, liquid and gas chromatography and flow cytometry
- Computing resources
Microbes and their insect vectors
We study many different organisms that are important models for disease or disease transmission including:
- Archaea (Asgard species, Sulfolobus) and yeasts (Saccharomyces)
- Insect vectors of medical and veterinary importance (Aedes & Anopheles mosquitoes, midges, sand flies, Tsetse flies)
- Nematodes (Caenorhabditis, Trichuris)
- Parasitic trypanosomes (Leishmania, Trypanosoma brucei, Trypanosoma congolense, Trypanosoma cruzi)
- Pathogenic and commensal gut microbes (Bifidobacteria, Enterococci, Escherichia, Mycobacteria, Pseudomonadaceae)
- Protozoa (Amoebae, Tetrahymena)
- Viruses of concern (Coronaviruses including SARS-COV-2, Ebola , HIV, Influenza)
We actively collaborate with academics across different faculties at Lancaster University, as well as with industry and third sector stake holders. If you are interested in establishing a new collaboration please contact the researcher(s) with the most appropriate expertise from the list on this page.
There are opportunities to contribute to the research within the theme for undergraduate students through research projects and funded summer internships.
Lancaster researcher talks about the history of medicinal drugs for museum podcast
The use of medicinal drugs derived from plants is the topic of a podcast by Lancaster University researcher Dr Karen Wright as part of a series of local history podcasts and exhibitions to mark a hundred years of Lancaster City Museums.