Professor Aneta Stefanovska
ProfessorResearch Interests
My work is motivated by the question “What are the physical principles underlying living systems?”. Living systems are characterised by their ability to respond to fluctuations coming from the external and internal environments. They exchange energy and matter with their environments and often do so in a regular way. Hence they have mechanisms to stabilise the frequency and amplitude of the associated oscillations, and can be characterised as interacting self-sustained non-autonomous oscillators.
We have named this class of systems chronotaxic (from chronos – time and taxis – order) and we are now defining their properties. We also work on the development of the numerical methods needed for studying the dynamics of chronotaxic systems as an inverse problem. Analysing recorded data, we observe similar patterns at all levels of complexity: starting from cells up to the cardiovascular system and the brain, to ecosystems and climate. Similar properties were observed also in laboratory experiments on surface state electrons on liquid helium.
In my work I learn from nature, but I also try to be useful to nature. Recording time-series, and analysing the underlying dynamics with our new algorithms, we investigate how we age in a dynamical sense, or what happens when we are unconsciousness in anaesthesia, or what changes take place in various cardiovascular diseases. Recently, we started investigating the dynamical markers of cancer.
Network dynamics-based standards for endothelial health
13/11/2023 → 01/11/2024
Research
Network dynamics-based standards for endothelial health
01/11/2023 → 31/03/2025
Research
Creation and evolution of quantum turbulence in novel geometries
23/01/2023 → 22/01/2027
Research
DSI:Quantitative Assessment of Autistic Spectrum Disorder
01/10/2021 → 31/03/2025
Research
Alzheimer's Research Project - Years 11,12 & 13
01/10/2019 → 30/09/2022
Research
Workshop on non-autonomous oscillatory systems and their applications in the life sciences
01/06/2018 → 30/11/2019
Research
Conduction and selectivity between monovalent ions within the potassium channel
01/11/2017 → 30/10/2021
Research
A device to detect and measure the progression of dementia by quantifying the interactions between neuronal and cardiovascular oscillations
01/05/2015 → 31/10/2018
Research
Ionic Coulomb blockade oscillations and the physical origins of permeation, selectivity, and their mutation transformations in biological ion channels
01/04/2015 → 30/09/2018
Research
H2020: COSMOS
01/01/2015 → 31/08/2019
Research
Physics of non-autonomous systems in the life sciences
01/05/2011 → 31/03/2015
Research
Interdiciplinary workshop on fluctuations and coherence: from superfluids to living systems
01/04/2011 → 31/03/2012
Research
University Hospitals of Morecambe Bay NHS Foundation Trust funded (Leese bequest) studentship - Modelling the role of the endothelium in cardiovascular physiology £61,000
01/09/2010 → 31/08/2013
Research
Dynamics of cardiovascular ageing
01/10/2009 → 31/03/2012
Research
FEC code for PYA7886: Dynamics of cardiovascular ageing
01/10/2009 → …
Research
FP6 BRACCIA; Brain, respiration and cardiac causalities in anaesthesia
01/01/2005 → 01/09/2009
Other
Workshop on Time Series Analysis of Noisy Data (TSAND)
01/01/1900 → …
Research
Noisy oscillators in biology and medicine
Invited talk
Workshop on time-series analysis of noisy data
Participation in workshop, seminar, course
Interactions in oscillatory systems far from equilibrium
Public Lecture/ Debate/Seminar
Multiscale oscillatory dynamics: What happens when the frequencies are not constant?
Invited talk
Non-Equilibrium Oscillatory Dynamics of Electrons on the Surface of Liquid Helium
Invited talk
Exploring the deterministic properties of external perturbations in data from open systems
Invited talk
Coupled oscillatory processes from a cell to the brain
Invited talk
Brain, respiratory and cardiac causalities: lessons from anaesthesia with sevoflorane and propofol
Invited talk
Cardiovascular and brain interactions in dementia
Invited talk
Phase dynamics – Theory and applications
Invited talk
Noise in open systems
Invited talk
Transitions in systems with non-autonomous perturbations: lessons from cell energy metabolism
Invited talk
Understanding real-world systems from the perspective of time-varying dynamics
Invited talk
Physics of biological rhythms: Challenges and applications
Invited talk
Where are we with the understanding of a collective dynamics of quasi-periodically perturbed particles?
Invited talk
Coherence and couplings between cardiac, respiratory and myogenic rhythms
Invited talk
Why is it important to study the oscillations of cardiovascular system?
Invited talk
Why is it important to study the oscillation of cardiovascular system?
Invited talk
Stability in networks of open systems
Invited talk
Chronotaxic dynamics: when the characteristic frequencies fluctuate and the system is stable
Invited talk
Complex and stable dynamics emerging from noise
Invited talk
Biological cell as a chronotaxic system
Invited talk
Oscillatory components of microvascular blood flow and their physiological relevance
Invited talk
Stability in the Fluctuations of the Cell Membrane Potential and How They Change with Cancer
Invited talk
Systems That Can Stabilise Their Rates: Lessons from the Circulatory System
Invited talk
Foundations of chronotaxic systems and applications to living systems
Invited talk
Chronotaxic systems: What and why?
Invited talk
Fluctuations in the membrane potential of a living cell: Chronotaxic systems – Stability in complexity
Invited talk
Nonlinear and Biomedical Physics
- DSI - Health
- Nonlinear and Biomedical Physics