Dr Tom Palmer

Lecturer in Statistics

PhD Supervision Interests

Mendelian randomization, instrumental variables, meta-analysis, structural equation models.

Reading comprehension difficulties in children with rolandic epilepsy
Currie, N.K., Lew, A.R., Palmer, T.M., Basu, H., De Goede, C., Ayer, A., Cain, K. 14/12/2017 In: Developmental Medicine and Child Neurology. 9 p.
Journal article

Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery
Cook, J., Maclennan, G., Palmer, T., Lois, N., Emsley, R. 20/11/2017 In: Journal of Clinical Epidemiology.
Journal article

Correcting the standard errors of two-stage residual inclusion estimators for Mendelian randomization studies
Palmer, T.M., Holmes, M.V., Keating, B.J., Sheehan, N.A. 1/11/2017 In: American Journal of Epidemiology. 186, 9, p. 1104-1114. 11 p.
Journal article

Education and coronary heart disease: mendelian randomisation study
Tillmann, T., Vaucher, J., Okbay, A., Pikhart, H., Peasey, A., Kubinova, R., Pajak, A., Tamosiunas, A., Malyutina, S., Hartwig, F.P., Fischer, K., Veronesi, G., Palmer, T., Bowden, J., Davey Smith, G., Bobak, M., Holmes, M.V. 30/08/2017 In: BMJ. 358, 10 p.
Journal article

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis
Roetker, N., Armasu, S.M., Pankow, J.S., Lutsey, P.L., Tang, W., Rosenberg, M.A., Palmer, T.M., MacLehose, R.F., Heckbert, S.R., Cushman, M., de Andrade, M., Folsom, A.R. 07/2017 In: Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343. 10 p.
Journal article

Using instrumental variable methods for a binary outcome to address non-compliance in a randomised trial: application to a surgical trial
Cook, J., MacLennan, G., Palmer, T.M., Lois, N., Emsley, R. 15/06/2017 In: Journal of Clinical Epidemiology.
Journal article

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian randomization analysis
Dale, C., Fatemifar, G., Palmer, T., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J.E.L., Shah, T., Wong, A., Warren, H.R., McLachlan, S., Trompet, S., Moldovan, M., Morris, R.W., Sofat, R., Kumari, M., Hyppönen, E., Jefferis, B.J., Gaunt, T.R., Ben-Shlomo, Y., Zhou, A., Gentry-Maharaj, A., Ryan, A., de Mutsert, R., Noordam, R., Caulfield, M.J., Jukema, J.W., Worrall, B.B., Munroe, P.B., Menon, U., Power, C., Kuh, D., Lawlor, D.A., Humphries, S.E., Mook-Kanamori, D.O., Davey Smith, G., Sattar, N., Kivimaki, M., Price, J.F., Dudbridge, F., Hingorani, A.D., Holmes, M.V., Casas, J. 13/06/2017 In: Circulation. 135, 24, p. 2373-2388. 16 p.
Journal article

Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity: a Mendelian randomisation study
Richmond, R., Timpson, N.J., Felix, J., Palmer, T.M., Gaillard, R., McMahon, G., Davey Smith, G., Jaddoe, V., Lawlor, D.A. 24/01/2017 In: PLoS Medicine. 14, 1, 24 p.
Journal article

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis
EPIC-Netherland Investigators, UCLEB Investigators, IN Day 12/2016 In: International Journal of Epidemiology. 45, 6, p. 1927-1937. 11 p.
Journal article

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels
Bonilla, C., Lewis, S.J., Rowlands, M., Gaunt, T.R., Smith, G.D., Gunnell, D., Palmer, T., Donovan, J.L., Hamdy, F.C., Neal, D.E., Eeles, R., Easton, D., Kote-Jarai, Z., Olama, A.A.A., Benlloch, S., Muir, K., Giles, G.G., Wiklund, F., Gronberg, H., Haiman, C.A., Schleutker, J., Nordestgaard, B.G., Travis, R.C., Pashayan, N., Khaw, K., Stanford, J.L., Blot, W.J., Thibodeau, S., Maier, C., Kibel, A.S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M.R., Pandha, H., Lathrop, M., Martin, R.M., Holly, J.M.P., PRACTICAL consortium 1/10/2016 In: International Journal of Cancer. 139, 7, p. 1520-1533. 14 p.
Journal article

Antipsychotic prescribing in care homes before and after launch of a national dementia strategy: an observational study in English institutions over a 4-year period
Szczepura, A., Wild, D., Khan, A., Owen, D., Palmer, T.M., Muhammad, T., Clark, M., Bowman, C. 20/09/2016 In: BMJ Open. 6, 9, 11 p.
Journal article

Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk
Tragante, V., Asselbergs, F.W., Swerdlow, D.I., Palmer, T.M., Moore, J.H., Bakker, P.I.W., Keating, B.J., Holmes, M.V. 05/2016 In: Human Genetics. 135, 5, p. 453-467. 15 p.
Journal article

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis
White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F.A., Giambartolomei, C., Swerdlow, D.I., Palmer, T., McLachlan, S., Langenberg, C., Zabaneh, D., Lovering, R., Cavadino, A., Jefferis, B., Finan, C., Wong, A., Amuzu, A., Ong, K., Gaunt, T.R., Warren, H., Davies, T., Drenos, F., Cooper, J., Ebrahim, S., Lawlor, D.A., Talmud, P.J., Humphries, S.E., Power, C., Hypponen, E., Richards, M., Hardy, R., Kuh, D., Wareham, N., Ben-Shlomo, Y., Day, I.N., Whincup, P., Morris, R., Strachan, M.W.J., Price, J., Kumari, M., Kivimaki, M., Plagnol, V., Whittaker, J.C., Smith, G.D., Dudbridge, F., Casas, J.P., Holmes, M.V., Hingorani, A.D. 04/2016 In: The Lancet Diabetes and Endocrinology. 4, 4, p. 327-336. 10 p.
Journal article

Genetic evidence for causal relationships between maternal obesity-related traits and birth weight
Tyrrell, J., Richmond, R.C., Palmer, T. 15/03/2016 In: Journal of the American Medical Association. 315, 11, p. 1129-1140. 12 p.
Journal article

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array
Rodriguez, S., Gaunt, T.R., Guo, Y., Zheng, J., Barnes, M.R., Tang, W., Danish, F., Johnson, A., Castillo, B.A., Li, Y.R., Hakonarson, H., Buxbaum, S.G., Palmer, T., Tsai, M.Y., Lange, L.A., Ebrahim, S., Davey Smith, G., Lawlor, D.A., Folsom, A.R., Hoogeveen, R., Reiner, A., Keating, B., Day, I.N. 01/2016 In: European Journal of Human Genetics. 24, 1, p. 106-112. 7 p.
Journal article

Meta-analysis in Stata: an updated collection from the Stata Journal
Palmer, T., Sterne, J.A.C. 2016 2nd ed. ed. Stata Press. 534 p. ISBN: 1597181471, 9781597181471.
Book

Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches
North, T., Palmer, T.M., Lewis, S.J., Cooper, R., Power, C., Pattie, A., Starr, J.M., Deary, I.J., Martin, R.M., Aihie Sayer, A., Kumari, M., Cooper, C., Kivimaki, M., Kuh, D., Ben-Shlomo, Y., Day, I.N.M. 15/12/2015 In: BMJ Open. 5, 12, 13 p.
Journal article

A Mendelian randomization study of circulating uric acid and type 2 diabetes
Sluijs, I., Holmes, M.V., van der Schouw, Y.T., Beulens, J.W.J., Asselbergs, F.W., Huerta, J.M., Palmer, T.M., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Clavel-Chapelon, F., Fagherazzi, G., Franks, P.W., Gavrila, D., Kaaks, R., Khaw, K.T., Kühn, T., Molina-Montes, E., Mortensen, L.M., Nilsson, P.M., Overvad, K., Palli, D., Panico, S., Quirós, J.R., Rolandsson, O., Sacerdote, C., Sala, N., Schmidt, J.A., Scott, R.A., Sieri, S., Slimani, N., Spijkerman, A.M., Tjonneland, A., Travis Dphil, R.C., Tumino, R., van der A, D.L., Sharp, S.J., Forouhi, N.G., Langenberg, C., Riboli, E., Wareham, N.J., InterAct consortium 08/2015 In: Diabetes. 64, 8, p. 3028-3036. 9 p.
Journal article

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium
Shungin, D., Cornelis, M.C., Divaris, K., Holtfreter, B., Shaffer, J.R., Yu, Y., Barros, S.P., Beck, J.D., Biffar, R., Boerwinkle, E.A., Crout, R.J., Ganna, A., Hallmans, G., Hindy, G., Hu, F.B., Kraft, P., McNeil, D.W., Melander, O., Moss, K.L., North, K.E., Orho-Melander, M., Pedersen, N.L., Ridker, P.M., Rimm, E.B., Rose, L.M., Rukh, G., Teumer, A., Weyant, R.J., Chasman, D.I., Joshipura, K., Kocher, T., Magnusson, P.K.E., Marazita, M.L., Nilsson, P., Offenbacher, S., Davey Smith, G., Lundberg, P., Palmer, T.M., Timpson, N.J., Johansson, I., Franks, P.W. 6/06/2015 In: International Journal of Epidemiology. 44, 2, p. 638-650. 13 p.
Journal article

Mendelian randomization of blood lipids for coronary heart disease
Holmes, M.V., Asselbergs, F.W., Palmer, T.M., Drenos, F., Lanktree, M.B., Nelson, C.P., Dale, C.E., Padmanabhan, S., Finan, C., Swerdlow, D.I., Tragante, V., van Iperen, E.P.A., Sivapalaratnam, S., Shah, S., Elbers, C.C., Shah, T., Engmann, J., Giambartolomei, C., White, J., Zabaneh, D., Sofat, R., McLachlan, S., Doevendans, P.A., Balmforth, A.J., Hall, A.S., North, K.E., Almoguera, B., Hoogeveen, R.C., Cushman, M., Fornage, M., Patel, S.R., Redline, S., Siscovick, D.S., Tsai, M.Y., Karczewski, K.J., Hofker, M.H., Verschuren, W.M., Bots, M.L., van der Schouw, Y.T., Melander, O., Dominiczak, A.F., Morris, R., Ben-Shlomo, Y., Price, J., Kumari, M., Baumert, J., Peters, A., Thorand, B., Koenig, W., Gaunt, T.R., Humphries, S.E., Clarke, R., Watkins, H., Farrall, M., Wilson, J.G., Rich, S.S., de Bakker, P.I.W., Lange, L.A., Davey Smith, G., Reiner, A.P., Talmud, P.J., Kivimäki, M., Lawlor, D.A., Dudbridge, F., Samani, N.J., Keating, B.J., Hingorani, A.D., Casas, J.P., UCLEB Consortium 1/03/2015 In: European Heart Journal. 36, 9, p. 539-550. 12 p.
Journal article

Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women
Cartwright, R., Kirby, A.C., Tikkinen, K.A.O., Mangera, A., Thiagamoorthy, G., Rajan, P., Pesonen, J., Ambrose, C., Gonzalez-Maffe, J., Bennett, P., Palmer, T., Walley, A., Järvelin, M., Chapple, C., Khullar, V. 02/2015 In: American Journal of Obstetrics and Gynecology. 212, 2, p. 199.e1-24. 24 p.
Journal article

Estimating structural mean models with multiple instrumental variables using the generalised method of moments
Clarke, P., Palmer, T.M., Windmeijer, F. 2015 In: Statistical Science. 30, 1, p. 96-117. 22 p.
Journal article

Fitting fixed- and random-effects meta-analysis models using structural equation modeling with the sem and gsem commands
Palmer, T., Sterne, J.A.C. 2015 In: Stata Journal. 15, 3, p. 645-671. 27 p.
Journal article

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits
Silverwood, R.J., Holmes, M.V., Dale, C.E., Lawlor, D.A., Whittaker, J.C., Smith, G.D., Leon, D.A., Palmer, T., Keating, B.J., Zuccolo, L., Casas, J.P., Dudbridge, F., Alcohol-ADH1B Consortium 12/2014 In: International Journal of Epidemiology. 43, 6, p. 1781-1790. 10 p.
Journal article

Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men
Cartwright, R., Mangera, A., Tikkinen, K.A.O., Rajan, P., Pesonen, J., Kirby, A.C., Thiagamoorthy, G., Ambrose, C., Gonzalez-Maffe, J., Bennett, P.R., Palmer, T., Walley, A., Järvelin, M., Khullar, V., Chapple, C. 10/2014 In: European Urology. 66, 4, p. 752-768. 17 p.
Journal article

Alcohol consumption and cognitive performance: a Mendelian randomization study
Kumari, M., Holmes, M.V., Dale, C.E., Hubacek, J.A., Palmer, T.M., Pikhart, H., Peasey, A., Britton, A., Horvat, P., Kubinova, R., Malyutina, S., Pajak, A., Tamosiunas, A., Shankar, A., Singh-Manoux, A., Voevoda, M., Kivimaki, M., Hingorani, A.D., Marmot, M.G., Casas, J.P., Bobak, M. 09/2014 In: Addiction. 109, 9, p. 1462-1471. 10 p.
Journal article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Holmes, M.V., Dale, C.E., Zuccolo, L., Silverwood, R.J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., Cavadino, A., Drogan, D., Padmanabhan, S., Li, S., Yesupriya, A., Leusink, M., Sundstrom, J., Hubacek, J.A., Pikhart, H., Swerdlow, D.I., Panayiotou, A.G., Borinskaya, S.A., Finan, C., Shah, S., Kuchenbaecker, K.B., Shah, T., Engmann, J., Folkersen, L., Eriksson, P., Ricceri, F., Melander, O., Sacerdote, C., Gamble, D.M., Rayaprolu, S., Ross, O.A., McLachlan, S., Vikhireva, O., Sluijs, I., Scott, R.A., Adamkova, V., Flicker, L., Bockxmeer, F.M.v., Power, C., Marques-Vidal, P., Meade, T., Marmot, M.G., Ferro, J.M., Paulos-Pinheiro, S., Humphries, S.E., Talmud, P.J., Mateo Leach, I., Verweij, N., Linneberg, A., Skaaby, T., Doevendans, P.A., Cramer, M.J., van der Harst, P., Klungel, O.H., Dowling, N.F., Dominiczak, A.F., Kumari, M., Nicolaides, A.N., Weikert, C., Boeing, H., Ebrahim, S., Gaunt, T.R., Price, J.F., Lannfelt, L., Peasey, A., Kubinova, R., Pajak, A. 10/07/2014 In: BMJ. 349, 16 p.
Journal article

Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study
Granell, R., Henderson, A.J., Evans, D.M., Smith, G.D., Ness, A.R., Lewis, S., Palmer, T.M., Sterne, J.A.C. 1/07/2014 In: PLoS Medicine. 11, 7, 14 p.
Journal article

Lack of identification in semiparametric instrumental variable models with binary outcomes
Burgess, S., Granell, R., Palmer, T.M., Sterne, J.A.C., Didelez, V. 1/07/2014 In: American Journal of Epidemiology. 180, 1, p. 111-119. 9 p.
Journal article

Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis
Patel, R.S., Asselbergs, F.W., Quyyumi, A.A., Palmer, T.M., Finan, C.I., Tragante, V., Deanfield, J., Hemingway, H., Hingorani, A.D., Holmes, M.V. 3/06/2014 In: Journal of the American College of Cardiology. 63, 21, p. 2234-2245. 12 p.
Journal article

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis
Holmes, M.V., Lange, L.A., Palmer, T., Lanktree, M.B., North, K.E., Almoguera, B., Buxbaum, S., Chandrupatla, H.R., Elbers, C.C., Guo, Y., Hoogeveen, R.C., Li, J., Li, Y.R., Swerdlow, D.I., Cushman, M., Price, T.S., Curtis, S.P., Fornage, M., Hakonarson, H., Patel, S.R., Redline, S., Siscovick, D.S., Tsai, M.Y., Wilson, J.G., van der Schouw, Y.T., FitzGerald, G.A., Hingorani, A.D., Casas, J.P., de Bakker, P.I.W., Rich, S.S., Schadt, E.E., Asselbergs, F.W., Reiner, A.P., Keating, B.J. 6/02/2014 In: American Journal of Human Genetics. 94, 2, p. 198-208. 11 p.
Journal article

Effects of promoting longer-term and exclusive breastfeeding on cardiometabolic risk factors at age 11.5 years: a cluster-randomized, controlled trial
Martin, R.M., Patel, R., Kramer, M.S., Vilchuck, K., Bogdanovich, N., Sergeichick, N., Gusina, N., Foo, Y., Palmer, T., Thompson, J., Gillman, M.W., Smith, G.D., Oken, E. 21/01/2014 In: Circulation. 129, 3, p. 321-329. 9 p.
Journal article

Prospective associations of parental smoking, alcohol use, marital status, maternal satisfaction, and parental and childhood body mass index at 6.5 years with later problematic eating attitudes
Wade, K.H., Skugarevsky, O., Kramer, M.S., Patel, S.R., Bogdanovich, N., Vilchuck, K., Sergeichick, N., Richmond, R., Palmer, T., Davey Smith, G., Gillman, M., Oken, E., Martin, R.M. 6/01/2014 In: Nutrition and Diabetes. 4, 8 p.
Journal article

Estimating adjusted associations between random effects from multilevel models: the reffadjust package
Palmer, T., Macdonald-Wallis, C., Lawlor, D., Tilling, K. 2014 In: Stata Journal. 14, 1, p. 119-140. 22 p.
Journal article

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study
Holmes, M.V., Simon, T., Exeter, H.J., Folkersen, L., Asselbergs, F.W., Guardiola, M., Cooper, J.A., Palmen, J., Hubacek, J.A., Carruthers, K.F., Horne, B.D., Brunisholz, K.D., Mega, J.L., van Iperen, E.P.A., Li, M., Leusink, M., Trompet, S., Verschuren, J.J.W., Hovingh, G.K., Dehghan, A., Nelson, C.P., Kotti, S., Danchin, N., Scholz, M., Haase, C.L., Rothenbacher, D., Swerdlow, D.I., Kuchenbaecker, K.B., Staines-Urias, E., Goel, A., van 't Hooft, F., Gertow, K., de Faire, U., Panayiotou, A.G., Tremoli, E., Baldassarre, D., Veglia, F., Holdt, L.M., Beutner, F., Gansevoort, R.T., Navis, G.J., Mateo Leach, I., Breitling, L.P., Brenner, H., Thiery, J., Dallmeier, D., Franco-Cereceda, A., Boer, J.M.A., Stephens, J.W., Hofker, M.H., Tedgui, A., Hofman, A., Uitterlinden, A.G., Adamkova, V., Pitha, J., Onland-Moret, N.C., Cramer, M.J., Nathoe, H.M., Spiering, W., Klungel, O.H., Kumari, M., Whincup, P.H., Morrow, D.A., Braund, P.S., Hall, A.S., Olsson, A.G., Doevendans, P.A., Trip, M.D., Tobin 19/11/2013 In: Journal of the American College of Cardiology. 62, 21, p. 1966-1976. 11 p.
Journal article

Effects of an intervention to promote breastfeeding on maternal adiposity and blood pressure at 11.5 y postpartum: results from the Promotion of Breastfeeding Intervention Trial, a cluster-randomized controlled trial
Oken, E., Patel, R., Guthrie, L.B., Vilchuck, K., Bogdanovich, N., Sergeichick, N., Palmer, T.M., Kramer, M.S., Martin, R.M. 10/2013 In: American Journal of Clinical Nutrition. 98, 4, p. 1048-1056. 9 p.
Journal article

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
Palmer, T.M., Nordestgaard, B.G., Benn, M., Tybjærg-Hansen, A., Davey Smith, G., Lawlor, D.A., Timpson, N.J. 18/07/2013 In: BMJ. 347, 10 p.
Journal article

Associations of mortality with own height using son's height as an instrumental variable
Carslake, D., Fraser, A., Davey Smith, G., May, M., Palmer, T., Sterne, J., Silventoinen, K., Tynelius, P., Lawlor, D.A., Rasmussen, F. 07/2013 In: Economics and Human Biology. 11, 3, p. 351-359. 9 p.
Journal article

Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies
Harbord, R.M., Didelez, V., Palmer, T.M., Meng, S., Sterne, J.A.C., Sheehan, N.A. 30/03/2013 In: Statistics in Medicine. 32, 7, p. 1246-1258. 13 p.
Journal article

Effects of promoting increased duration and exclusivity of breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial
Martin, R.M., Patel, R., Kramer, M.S., Guthrie, L., Vilchuck, K., Bogdanovich, N., Sergeichick, N., Gusina, N., Foo, Y., Palmer, T., Rifas-Shiman, S.L., Gillman, M.W., Davey Smith, G., Oken, E. 13/03/2013 In: Journal of the American Medical Association. 309, 10, p. 1005-1013. 9 p.
Journal article

Multivariate multilevel spline models for parallel growth processes: application to weight and mean arterial pressure in pregnancy
Macdonald-Wallis, C., Lawlor, D.A., Palmer, T., Tilling, K. 20/11/2012 In: Statistics in Medicine. 31, 26, p. 3147-3164. 18 p.
Journal article

Re: "credible mendelian randomization studies: approaches for evaluating the instrumental variable assumptions"
Palmer, T.M., Ramsahai, R.R., Lawlor, D.A., Sheehan, N.A., Didelez, V. 1/09/2012 In: American Journal of Epidemiology. 176, 5, p. 457-458; author reply 458. 2 p.
Journal article

Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
Theodoratou, E., Palmer, T., Zgaga, L., Farrington, S.M., McKeigue, P., Din, F.V.N., Tenesa, A., Davey-Smith, G., Dunlop, M.G., Campbell, H. 6/06/2012 In: PLoS ONE. 7, 6, 10 p.
Journal article

Using multiple genetic variants as instrumental variables for modifiable risk factors
Palmer, T.M., Lawlor, D.A., Harbord, R.M., Sheehan, N.A., Tobias, J.H., Timpson, N.J., Davey Smith, G., Sterne, J.A.C. 06/2012 In: Statistical Methods in Medical Research. 21, 3, p. 223-242. 20 p.
Journal article

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure
Munafò, M.R., Timofeeva, M.N., Morris, R.W., Prieto-Merino, D., Sattar, N., Brennan, P., Johnstone, E.C., Relton, C., Johnson, P.C.D., Walther, D., Whincup, P.H., Casas, J.P., Uhl, G.R., Vineis, P., Padmanabhan, S., Jefferis, B.J., Amuzu, A., Riboli, E., Upton, M.N., Aveyard, P., Ebrahim, S., Hingorani, A.D., Watt, G., Palmer, T.M., Timpson, N.J., Davey Smith, G., EPIC Study Group 16/05/2012 In: JNCI: Journal of the National Cancer Institute. 104, 10, p. 740-748. 9 p.
Journal article

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach
Nordestgaard, B.G., Palmer, T.M., Benn, M., Zacho, J., Tybjaerg-Hansen, A., Davey Smith, G., Timpson, N.J. 1/05/2012 In: PLoS Medicine. 9, 5, 13 p.
Journal article

The causal roles of vitamin B(12) and transcobalamin in prostate cancer: can Mendelian randomization analysis provide definitive answers?
Collin, S.M., Metcalfe, C., Palmer, T.M., Refsum, H., Lewis, S.J., Smith, G.D., Cox, A., Davis, M., Marsden, G., Johnston, C., Lane, J.A., Donovan, J.L., Neal, D.E., Hamdy, F.C., Smith, A.D., Martin, R.M. 23/08/2011 In: International Journal of Molecular Epidemiology and Genetics. 2, 4, p. 316-327. 12 p.
Journal article

Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study
Lewis, S.J., Araya, R., Smith, G.D., Freathy, R., Gunnell, D., Palmer, T., Munafò, M. 19/07/2011 In: PLoS ONE. 6, 7, 5 p.
Journal article

Maternal and offspring adiposity-related genetic variants and gestational weight gain
Lawlor, D.A., Fraser, A., Macdonald-Wallis, C., Nelson, S.M., Palmer, T.M., Davey Smith, G., Tilling, K. 07/2011 In: American Journal of Clinical Nutrition. 94, 1, p. 149-155. 7 p.
Journal article

Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses
Palmer, T.M., Sterne, J.A.C., Harbord, R.M., Lawlor, D.A., Sheehan, N.A., Meng, S., Granell, R., Smith, G.D., Didelez, V. 15/06/2011 In: American Journal of Epidemiology. 173, 12, p. 1392-1403. 12 p.
Journal article

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults
Lawlor, D.A., Harbord, R.M., Tybjaerg-Hansen, A., Palmer, T.M., Zacho, J., Benn, M., Timpson, N.J., Smith, G.D., Nordestgaard, B.G. 05/2011 In: Journal of Internal Medicine. 269, 5, p. 525-537. 13 p.
Journal article

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance
De Silva, N.M.G., Freathy, R.M., Palmer, T.M., Donnelly, L.A., Luan, J., Gaunt, T., Langenberg, C., Weedon, M.N., Shields, B., Knight, B.A., Ward, K.J., Sandhu, M.S., Harbord, R.M., McCarthy, M.I., Smith, G.D., Ebrahim, S., Hattersley, A.T., Wareham, N., Lawlor, D.A., Morris, A.D., Palmer, C.N.A., Frayling, T.M. 03/2011 In: Diabetes Care. 60, 3, p. 1008-1018. 11 p.
Journal article

Nonparametric bounds for the causal effect in a binary instrumental variable model
Palmer, T.M., Ramsahai, R., Didelez, V., Sheehan, N.A. 2011 In: Stata Journal. 11, 3, p. 345-367. 23 p.
Journal article

Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk
Lewis, S.J., Murad, A., Chen, L., Davey Smith, G., Donovan, J., Palmer, T., Hamdy, F., Neal, D., Lane, J.A., Davis, M., Cox, A., Martin, R.M. 19/10/2010 In: PLoS ONE. 5, 10, 7 p.
Journal article

Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications
Moreno, S.G., Sutton, A.J., Turner, E.H., Abrams, K.R., Cooper, N.J., Palmer, T.M., Ades, A.E. 7/08/2009 In: BMJ. 339, 7 p.
Journal article

Meta-analysis of Mendelian randomization studies incorporating all three genotypes
Palmer, T.M., Thompson, J.R., Tobin, M.D. 30/12/2008 In: Statistics in Medicine. 27, 30, p. 6570-6582. 13 p.
Journal article

Common variation in the WNK1 gene and blood pressure in childhood: the Avon Longitudinal Study of Parents and Children
Tobin, M.D., Timpson, N.J., Wain, L.V., Ring, S., Jones, L.R., Emmett, P.M., Palmer, T.M., Ness, A.R., Samani, N.J., Smith, G.D., Burton, P.R. 11/2008 In: Hypertension. 52, 5, p. 974-979. 6 p.
Journal article

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses
Palmer, T.M., Thompson, J.R., Tobin, M.D., Sheehan, N.A., Burton, P.R. 10/2008 In: International Journal of Epidemiology. 37, 5, p. 1161-1168. 8 p.
Journal article

Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population
Tobin, M.D., Tomaszewski, M., Braund, P.S., Hajat, C., Raleigh, S.M., Palmer, T.M., Caulfield, M., Burton, P.R., Samani, N.J. 06/2008 In: Hypertension. 51, 6, p. 1658-1664. 7 p.
Journal article